ID Q9HNB5_HALSA Unreviewed; 401 AA.
AC Q9HNB5;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:AAG20305.1};
DE SubName: Full=Probable oxidoreductase (Iron-containing alcoholdehydrogenase family) {ECO:0000313|EMBL:DAC79054.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:DAC79054.1};
GN Name=adh1 {ECO:0000313|EMBL:AAG20305.1};
GN OrderedLocusNames=VNG_2171G {ECO:0000313|EMBL:AAG20305.1};
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG20305.1, ECO:0000313|Proteomes:UP000000554};
RN [1] {ECO:0000313|EMBL:AAG20305.1, ECO:0000313|Proteomes:UP000000554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC {ECO:0000313|Proteomes:UP000000554}, and NRC-1
RC {ECO:0000313|EMBL:AAG20305.1};
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN [2] {ECO:0000313|EMBL:DAC79054.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79054.1};
RX PubMed=18313895; DOI=.1016/j.ygeno.2008.01.001;
RA Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT R1 compared to that of strain NRC-1.";
RL Genomics 91:335-346(2008).
RN [3] {ECO:0000313|EMBL:DAC79054.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79054.1};
RX PubMed=26042526;
RA Pfeiffer F., Oesterhelt D.;
RT "A manual curation strategy to improve genome annotation: application to a
RT set of haloarchael genomes.";
RL Life 5:1427-1444(2015).
RN [4] {ECO:0000313|EMBL:DAC79054.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79054.1};
RA Pfeiffer F., Marchfelder A., Habermann B.H., Dyall-Smith M.;
RT "The genome of the Halobacterium salinarum type strain is closely related
RT to that of the laboratory strains NRC-1 and R1.";
RL Microbiol. Resour. Announc. 0:0-0(2019).
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DR EMBL; AE004437; AAG20305.1; -; Genomic_DNA.
DR EMBL; BK010829; DAC79054.1; -; Genomic_DNA.
DR PIR; E84367; E84367.
DR RefSeq; WP_010903607.1; NC_002607.1.
DR AlphaFoldDB; Q9HNB5; -.
DR SMR; Q9HNB5; -.
DR STRING; 64091.VNG_2171G; -.
DR PaxDb; 64091-VNG_2171G; -.
DR GeneID; 68694736; -.
DR KEGG; hal:VNG_2171G; -.
DR PATRIC; fig|64091.14.peg.1666; -.
DR HOGENOM; CLU_007207_0_0_2; -.
DR OrthoDB; 57329at2157; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd14866; Fe-ADH-like; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:DAC79054.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000554}.
FT DOMAIN 16..384
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 401 AA; 40447 MW; A91D8FBE4F79FA3E CRC64;
MSQSPAAFRF DYESPALRFG PDSVRDLDAS LDAHDADTAL VVTGSTVGTT PAVMDPVRDG
LGDRLAGVFA ETTGEKRLTT AFDAAERVAA TDADAIVAVG GGSSIDVATV AAALTGTTQS
RAAVARTVRD TATVPIPDGA LPPIVVVPTT LAGADISQGA GIAAHPDAGV VDDTHSAVAD
DRRLMPASVV ADPVLAATTP RSVLAGSAMN GLNKGIETLY AATATPITDA TASHGVGTLA
AGLRALGTAD PTPETMAPIL RGLLLVEYGI SRPDATTLSL THAFGHALSR ASPIQQGVAH
AVVTPHVLAH LFDSTDGRRD RLAAALDVGD DPDPASAVID AVTAVRDALG LPARLRDTDG
PARSELQAVA AAAVADPFVD NAPDGVPLTR ADATEILDAA W
//
