ID Q9HQ42_HALSA Unreviewed; 301 AA.
AC Q9HQ42;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN OrderedLocusNames=VNG_1340C {ECO:0000313|EMBL:AAG19675.1};
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG19675.1, ECO:0000313|Proteomes:UP000000554};
RN [1] {ECO:0000313|EMBL:AAG19675.1, ECO:0000313|Proteomes:UP000000554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC {ECO:0000313|Proteomes:UP000000554};
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; AE004437; AAG19675.1; -; Genomic_DNA.
DR PIR; G84288; G84288.
DR AlphaFoldDB; Q9HQ42; -.
DR STRING; 64091.VNG_1340C; -.
DR PaxDb; 64091-VNG_1340C; -.
DR KEGG; hal:VNG_1340C; -.
DR PATRIC; fig|64091.14.peg.1023; -.
DR HOGENOM; CLU_030571_3_2_2; -.
DR InParanoid; Q9HQ42; -.
DR OrthoDB; 7773at2157; -.
DR Proteomes; UP000000554; Chromosome.
DR CDD; cd07729; AHL_lactonase_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR42978:SF2; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42978; QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000554}.
FT DOMAIN 75..289
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 301 AA; 32892 MW; DBBFEBEC48A0FB4D CRC64;
MVVASPPPRI NLCQRLTTTG RFPRPNFGAA TSPPGVDVHY LDRGTITADR AYMIDSSTMA
TVADPDPEHA LVECPVYNLL IDHPKGTVLW DTGSHPDAGD GYWPTPLFEA FHHEDADEHT
LPAALADAGT AISDIDAVVA SHLHLDHAGG LRHFAGTDTP IYVHERELGY AYRSAATDTG
SIAYHSPDFD RALNWRVVAV DRGRRQLYPG LDLLHLPGHT PGLLGLYLEP EDGAAPAIVA
GDEAYQRENY EDGVPMATSL LSSLADWRES RRRVRDLARR TTADVFCGHD TRDAARLAAR
F
//
