ID Q9HSA8_HALSA Unreviewed; 392 AA.
AC Q9HSA8;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Bifunctional short chain isoprenyl diphosphate synthase {ECO:0000313|EMBL:AAG18899.1};
DE SubName: Full=Stomatin family protein {ECO:0000313|EMBL:DAC77591.1};
GN Name=ids {ECO:0000313|EMBL:AAG18899.1};
GN OrderedLocusNames=VNG_0321G {ECO:0000313|EMBL:AAG18899.1};
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG18899.1, ECO:0000313|Proteomes:UP000000554};
RN [1] {ECO:0000313|EMBL:AAG18899.1, ECO:0000313|Proteomes:UP000000554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC {ECO:0000313|Proteomes:UP000000554}, and NRC-1
RC {ECO:0000313|EMBL:AAG18899.1};
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN [2] {ECO:0000313|EMBL:DAC77591.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77591.1};
RX PubMed=18313895; DOI=.1016/j.ygeno.2008.01.001;
RA Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT R1 compared to that of strain NRC-1.";
RL Genomics 91:335-346(2008).
RN [3] {ECO:0000313|EMBL:DAC77591.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77591.1};
RX PubMed=26042526;
RA Pfeiffer F., Oesterhelt D.;
RT "A manual curation strategy to improve genome annotation: application to a
RT set of haloarchael genomes.";
RL Life 5:1427-1444(2015).
RN [4] {ECO:0000313|EMBL:DAC77591.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77591.1};
RA Pfeiffer F., Marchfelder A., Habermann B.H., Dyall-Smith M.;
RT "The genome of the Halobacterium salinarum type strain is closely related
RT to that of the laboratory strains NRC-1 and R1.";
RL Microbiol. Resour. Announc. 0:0-0(2019).
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DR EMBL; AE004437; AAG18899.1; -; Genomic_DNA.
DR EMBL; BK010829; DAC77591.1; -; Genomic_DNA.
DR PIR; G84191; G84191.
DR RefSeq; WP_010902193.1; NC_002607.1.
DR AlphaFoldDB; Q9HSA8; -.
DR STRING; 64091.VNG_0321G; -.
DR PaxDb; 64091-VNG_0321G; -.
DR GeneID; 68693266; -.
DR KEGG; hal:VNG_0321G; -.
DR PATRIC; fig|64091.14.peg.238; -.
DR HOGENOM; CLU_024949_2_0_2; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR43327; STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43327:SF10; STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000554};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..202
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
SQ SEQUENCE 392 AA; 42671 MW; CD4FDD4E59619A69 CRC64;
MYTALSVGTA GAAAADALPA AIFGGSLTTV VGLLLLVLLA VVVYETVQIV DAYEKQALTV
FGEYRGLLEP GINVIPPFVS RTYTFDMRTQ TIDVPRQEAI TRDNSPVTAD AVVYIRVRDA
KRAFLEVDDY KTAVSNLAQT TLRAVLGDME LDDTLNKRQE INSRIRTELD EPTDEWGIRV
ESVEVREVNP SQEVQQAMEQ QTSAERRRRA MILEAQGERQ SAIENAQGDK QSNIIRAQGE
KQSQILEAQG DAISTVLRAK SAESMGERAI IEKGMETLEG IGEGESNTFV LPQEVTSLVG
RYGKHLAGSD VGDGGSDLES MAFDEETREL IGLDNIDEIL NQITEEADVD PADLEEKAEA
VQRGEDAGLQ DAGEVIEEMD AELDDGTEDT GA
//
