ID Q9HTD1_PSEAE Unreviewed; 607 AA.
AC Q9HTD1;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Probable transcarboxylase subunit {ECO:0000313|EMBL:AAG08820.1};
GN OrderedLocusNames=PA5435 {ECO:0000313|EMBL:AAG08820.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG08820.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG08820.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
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DR EMBL; AE004091; AAG08820.1; -; Genomic_DNA.
DR PIR; F82966; F82966.
DR RefSeq; NP_254122.1; NC_002516.2.
DR RefSeq; WP_003105555.1; NZ_QZGE01000012.1.
DR AlphaFoldDB; Q9HTD1; -.
DR SMR; Q9HTD1; -.
DR STRING; 208964.PA5435; -.
DR PaxDb; 208964-PA5435; -.
DR GeneID; 77223971; -.
DR GeneID; 877876; -.
DR KEGG; pae:PA5435; -.
DR PATRIC; fig|208964.12.peg.5696; -.
DR PseudoCAP; PA5435; -.
DR HOGENOM; CLU_000395_4_2_6; -.
DR InParanoid; Q9HTD1; -.
DR OrthoDB; 9760256at2; -.
DR PhylomeDB; Q9HTD1; -.
DR BioCyc; PAER208964:G1FZ6-5562-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 10..270
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 531..606
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 607 AA; 66096 MW; 232AB0E9B935E010 CRC64;
MSNTIQAKKT GVTDTILRDA HQSLLATRMR TEDMLPICDK LDRVGYWSLE VWGGATFDAC
VRFLKEDPWE RLRKLKAALP NTRLQMLLRG QNLLGYRHYS DDVVRAFVAK AAVNGIDVFR
IFDAMNDVRN LRVSIEAVKA AGKHAQGTIC YTTSPVHTIE AFVAQGKAMA DMGVDSIAIK
DMAGLLTPYA TGDLVKALKD ALPLDVVVHS HDTAGVASMC QLKAVENGAD RIDTAISSMA
WGTSHPGTES MVAALRGTPY DTGLDLELIQ EIGMYFHAVR KKYHQFESEF TGVDTRVQVN
QVPGGMISNL ANQLKEQGAL NRMGEVLEEI PRVRADLGFP PLVTPTSQIV GTQAFFNVLA
GERYKTITNE VKLYLQGRYG KAPGEVNEQL RRQAIGSEEV IDVRPADLIK PELNKLRSEI
GNLAKSEEDV LTYAMFPDIG RKFLEEREAG TLKPEELLPI PTGKGVAAAG AEGTPTEFVI
DVHGETYRVD ITGVGVKSDN KRHFYLSIDG MPEEVVFEPL NEYVAGSASG RKHASEPGHV
STTMPGNIVD VLVKEGDSVK AGQAVLITEA MKMETEVQAG IAGTVKAIHV AKGDRVNPGE
ILIEIAG
//
