ID Q9HVI5_PSEAE Unreviewed; 334 AA.
AC Q9HVI5;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN OrderedLocusNames=PA4604 {ECO:0000313|EMBL:AAG07992.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG07992.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG07992.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; AE004091; AAG07992.1; -; Genomic_DNA.
DR PIR; F83070; F83070.
DR RefSeq; NP_253294.1; NC_002516.2.
DR RefSeq; WP_003094852.1; NZ_QZGE01000004.1.
DR AlphaFoldDB; Q9HVI5; -.
DR SMR; Q9HVI5; -.
DR STRING; 208964.PA4604; -.
DR PaxDb; 208964-PA4604; -.
DR GeneID; 881091; -.
DR KEGG; pae:PA4604; -.
DR PATRIC; fig|208964.12.peg.4819; -.
DR PseudoCAP; PA4604; -.
DR HOGENOM; CLU_017452_0_2_6; -.
DR InParanoid; Q9HVI5; -.
DR OrthoDB; 9808822at2; -.
DR PhylomeDB; Q9HVI5; -.
DR BioCyc; PAER208964:G1FZ6-4698-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 237..331
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 334 AA; 37256 MW; EF6A5A85AED1EC07 CRC64;
MSEVANDNHA PIPVTVLTGF LGAGKTTLLK YLLQAEHGMK IAVIENEYSE TPIDGQLLGV
EPVQVMTLSN GCVCCSINTD LEKALFLLLE RRDNGEIDFD RLVIECTGLA DPAPVAQTFF
ADEELCQRYV LDGIITLVDA ANAERHLQET IAQAQVGFAD RILVSKTDLV DAATFEALGQ
RLQRINRRAL VHVVEHGRID LAHLLDVRGF NLNADLGPGI GLRPLRAVAA KDSRDRIGTL
VLRSDTPLDL ERLSEFMDDL LQWHGNSLLR YKGVLNIADE PRRLVFQGVL RLYGFDWDSE
WRDDEARESV IVFIGDNLPE DSIREGFERI VEGR
//
