ID Q9HX89_PSEAE Unreviewed; 560 AA.
AC Q9HX89;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Probable medium-chain acyl-CoA ligase {ECO:0000313|EMBL:AAG07311.1};
GN OrderedLocusNames=PA3924 {ECO:0000313|EMBL:AAG07311.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG07311.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG07311.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
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DR EMBL; AE004091; AAG07311.1; -; Genomic_DNA.
DR PIR; A83155; A83155.
DR RefSeq; NP_252613.1; NC_002516.2.
DR RefSeq; WP_003103012.1; NZ_QZGE01000001.1.
DR AlphaFoldDB; Q9HX89; -.
DR SMR; Q9HX89; -.
DR STRING; 208964.PA3924; -.
DR PaxDb; 208964-PA3924; -.
DR GeneID; 879043; -.
DR KEGG; pae:PA3924; -.
DR PATRIC; fig|208964.12.peg.4112; -.
DR PseudoCAP; PA3924; -.
DR HOGENOM; CLU_000022_59_5_6; -.
DR InParanoid; Q9HX89; -.
DR OrthoDB; 9803968at2; -.
DR PhylomeDB; Q9HX89; -.
DR BioCyc; PAER208964:G1FZ6-3997-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd12119; ttLC_FACS_AlkK_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF11; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AAG07311.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 33..406
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 456..536
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 560 AA; 62316 MW; 1E49F252497DBD4E CRC64;
MLKTRLIPAA AGAYQYPLLI KSLMLSGRRY EKSHEIVYRD QVRYSYATFN ERVARLANVL
SEAGVKAGDT VAVMDWDSHR YLECMFAIPM IGAVLHTINI RLSPEQILYT MNHAEDRFVL
VNSEFVPLYQ AVAGQLATVE RTILLTDGAE KSAELPGLVG EYESLLAAAS PRYDFPDFDE
NSIATTFYTT GTTGNPKGVY FSHRQLVLHT LAMASTIGSL DSIRLLGTSD VYMPITPMFH
VHAWGTPYVA TMLGVKQVYP GRYDPELLVE LWKREKVTFS HCVPTILQMV MNARAAQGVD
FKGWKVIIGG SALNRSLYEA AKARGIQLTA AYGMSETCPL ISCAYLNDEL LAGSEDERTT
YRIKAGVPVP LVDAAIMDEQ GRFLPADGES QGELVLRSPW LTQGYFREPE RGEELWRGGW
MHTGDVATLD GMGFIEIRDR IKDVIKTGGE WLSSLELEDL ISRHPAVREV AVVGVPDPQW
GERPFALLVV REGQQLDARG LKEHLKPFVE QGNINKWAIP SQIAVVTDIP KTSVGKLDKK
RIRIEIAQWQ EAGSAFLSTV
//
