ID   Q9I2I4_PSEAE            Unreviewed;       675 AA.
AC   Q9I2I4;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 117.
DE   SubName: Full=Class III (Anaerobic) ribonucleoside-triphosphate reductase subunit, NrdD {ECO:0000313|EMBL:AAG05308.1};
GN   Name=nrdD {ECO:0000313|EMBL:AAG05308.1};
GN   OrderedLocusNames=PA1920 {ECO:0000313|EMBL:AAG05308.1};
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG05308.1, ECO:0000313|Proteomes:UP000002438};
RN   [1] {ECO:0000313|EMBL:AAG05308.1, ECO:0000313|Proteomes:UP000002438}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC   1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA   Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA   Hancock R.E., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004091; AAG05308.1; -; Genomic_DNA.
DR   PIR; D83405; D83405.
DR   RefSeq; NP_250610.1; NC_002516.2.
DR   RefSeq; WP_003111559.1; NZ_QZGE01000033.1.
DR   AlphaFoldDB; Q9I2I4; -.
DR   SMR; Q9I2I4; -.
DR   STRING; 208964.PA1920; -.
DR   PaxDb; 208964-PA1920; -.
DR   GeneID; 882172; -.
DR   KEGG; pae:PA1920; -.
DR   PATRIC; fig|208964.12.peg.2001; -.
DR   PseudoCAP; PA1920; -.
DR   HOGENOM; CLU_002707_0_2_6; -.
DR   InParanoid; Q9I2I4; -.
DR   OrthoDB; 9804622at2; -.
DR   PhylomeDB; Q9I2I4; -.
DR   BioCyc; PAER208964:G1FZ6-1960-MONOMER; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0031250; C:anaerobic ribonucleoside-triphosphate reductase complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:PseudoCAP.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IBA:GO_Central.
DR   GO; GO:0009265; P:2'-deoxyribonucleotide biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01675; RNR_III; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT   DOMAIN          11..100
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   675 AA;  76090 MW;  873978855781CB32 CRC64;
     MTQPRKATWP ATLLKRNGRE VPFDPGKIER AIAAAGQATG EFDPQQAQAL AERVVERLPE
     RACLDIERVQ DLVERVLMEA GHYPTARAYV VYRERHGRLR RERKTLVDVA ASMNEYLSRE
     DWRVRANANQ GYSLGGLILN VSGKVTANYW LDEVYDADIA AAHRDADLHI HDLDMLAGYC
     AGWSLRTLLN EGLNGVPGRV EAGPPKHLGS ALGQMVNFLG TLQNEWAGAQ AFSSFDTYLA
     PYVRKDRLDY ASVRQALQEF IYNLNVPSRW GTQTPFTNLT FDWVCPDDLR DQVPRIGGEE
     MPFAYGELQA EMDLINRAYI EVMQAGDAHG RVFTFPIPTY NITHDFPWDS DNATRLFEMT
     ARYGLPYFQN FLNSDMQPNQ VRSMCCRLQL DVRELLKRGN GLFGSAEQTG SLGVVTINCA
     RLGYRHRGDA AGLYRQLDHL LELAFASLEL KRKVIQQHMD AGLYPYTRRY LGTLRNHFST
     IGVNGLHEMV RNFSDDREGL HSEAGREMAL ALLDHVRARL VGFQEDSGHL YNLEATPAEG
     TTYRFAREDR KRYPRILQAG TPEAPYYTNS SQLPVGFTDD PFEALELQDA LQCKYTGGTV
     LHLYMAERIS SAEACKTLVR TALGRFRLPY LTVTPTFSIC PRHGYLAGEH EFCPKCDEEL
     LQRSTPKSCC GGCGG
//