ID Q9I2Q7_PSEAE Unreviewed; 552 AA.
AC Q9I2Q7;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=Sulfite reductase {ECO:0000313|EMBL:AAG05227.1};
GN Name=cysI {ECO:0000313|EMBL:AAG05227.1};
GN OrderedLocusNames=PA1838 {ECO:0000313|EMBL:AAG05227.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG05227.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG05227.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
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DR EMBL; AE004091; AAG05227.1; -; Genomic_DNA.
DR PIR; F83417; F83417.
DR RefSeq; NP_250529.1; NC_002516.2.
DR RefSeq; WP_003098180.1; NZ_QZGE01000003.1.
DR AlphaFoldDB; Q9I2Q7; -.
DR SMR; Q9I2Q7; -.
DR STRING; 208964.PA1838; -.
DR PaxDb; 208964-PA1838; -.
DR GeneID; 878581; -.
DR KEGG; pae:PA1838; -.
DR PATRIC; fig|208964.12.peg.1908; -.
DR PseudoCAP; PA1838; -.
DR HOGENOM; CLU_015667_1_0_6; -.
DR InParanoid; Q9I2Q7; -.
DR OrthoDB; 3189055at2; -.
DR PhylomeDB; Q9I2Q7; -.
DR BioCyc; PAER208964:G1FZ6-1876-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0009337; C:sulfite reductase complex (NADPH); IBA:GO_Central.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050311; F:sulfite reductase (ferredoxin) activity; IBA:GO_Central.
DR GO; GO:0016002; F:sulfite reductase activity; IBA:GO_Central.
DR GO; GO:0009970; P:cellular response to sulfate starvation; IDA:PseudoCAP.
DR GO; GO:0000103; P:sulfate assimilation; IBA:GO_Central.
DR Gene3D; 3.90.480.20; -; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 2.
DR Gene3D; 3.90.480.10; Sulfite Reductase Hemoprotein;Domain 2; 1.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045169; NO2/SO3_Rdtase_4Fe4S_prot.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR PANTHER; PTHR11493:SF47; SULFITE REDUCTASE [NADPH] SUBUNIT BETA; 1.
DR PANTHER; PTHR11493; SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED; 1.
DR Pfam; PF01077; NIR_SIR; 2.
DR Pfam; PF03460; NIR_SIR_ferr; 2.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 2.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 2.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 53..109
FT /note="Nitrite/Sulfite reductase ferredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF03460"
FT DOMAIN 119..272
FT /note="Nitrite/sulphite reductase 4Fe-4S"
FT /evidence="ECO:0000259|Pfam:PF01077"
FT DOMAIN 336..398
FT /note="Nitrite/Sulfite reductase ferredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF03460"
FT DOMAIN 411..547
FT /note="Nitrite/sulphite reductase 4Fe-4S"
FT /evidence="ECO:0000259|Pfam:PF01077"
SQ SEQUENCE 552 AA; 62132 MW; BD1228E60DAE1EDC CRC64;
MYVYDEYDQR IVEDRVKQFR DQTRRYLAGE LTGEEFRPLR LQNGLYIQRY APMLRIAVPY
GLLSSRQLRK LAQIARDYDK GYAHISTRQN VQFNWPELED VPEILAELAT VQMHAIQTSG
NCIRNTTTDQ FAGVARDELV DPRPWCEIIR QWSTFHPEFA HLPRKFKIAV NGAVSDRAAI
EVHDIGLEAV KNEAGELGFR VSVGGGLGRT PIVGSFINEF LPWQHLLGYL DAILRVYNRY
GRRDNKYKAR IKILVKALTP EVFAERVEAE WANLKDGPST LTEAEVQRVA AHFVDPAYKA
LDDLDESLAR LDAEHPGFAR WRARNTFAHK KPGYVAVTLS LKPTGTAPGD VTDKQLEAIA
DLADRYSFGE VRNSHNQNII LADVEQGELF ALWGELRELG FATPNVGLLT DIICCPGGDF
CSLANAKSIP IAEAIQRRFD NLDYLFDIGD IDLNISGCMN ACGHHHVGHI GILGVDKKGA
EFYQVSLGGS SARDASLGQI LGPSFAQEQM ADVIDKIIQV YVERRTEEEP FIDTFRRIGI
DPFKERVYAA NH
//
