ID Q9I3B4_PSEAE Unreviewed; 146 AA.
AC Q9I3B4;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE RecName: Full=HTH hxlR-type domain-containing protein {ECO:0000259|PROSITE:PS51118};
GN OrderedLocusNames=PA1607 {ECO:0000313|EMBL:AAG04996.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG04996.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG04996.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
RN [2] {ECO:0007829|PDB:2F2E}
RP X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH GLUCOSE.
RX PubMed=17322537; DOI=10.1110/ps.062668207;
RA Sieminska E.A., Xu X., Savchenko A., Sanders D.A.;
RT "The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A
RT resolution--a putative transcription factor.";
RL Protein Sci. 16:543-549(2007).
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DR EMBL; AE004091; AAG04996.1; -; Genomic_DNA.
DR PIR; G83445; G83445.
DR RefSeq; NP_250298.1; NC_002516.2.
DR RefSeq; WP_003087468.1; NZ_QZGE01000003.1.
DR PDB; 2F2E; X-ray; 1.85 A; A/B=1-146.
DR PDBsum; 2F2E; -.
DR AlphaFoldDB; Q9I3B4; -.
DR SMR; Q9I3B4; -.
DR STRING; 208964.PA1607; -.
DR PaxDb; 208964-PA1607; -.
DR DNASU; 881971; -.
DR GeneID; 881971; -.
DR KEGG; pae:PA1607; -.
DR PATRIC; fig|208964.12.peg.1667; -.
DR PseudoCAP; PA1607; -.
DR HOGENOM; CLU_111585_0_1_6; -.
DR InParanoid; Q9I3B4; -.
DR OrthoDB; 9807069at2; -.
DR PhylomeDB; Q9I3B4; -.
DR BioCyc; PAER208964:G1FZ6-1637-MONOMER; -.
DR EvolutionaryTrace; Q9I3B4; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR002577; HTH_HxlR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33204; TRANSCRIPTIONAL REGULATOR, MARR FAMILY; 1.
DR PANTHER; PTHR33204:SF26; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01638; HxlR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51118; HTH_HXLR; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:2F2E};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..108
FT /note="HTH hxlR-type"
FT /evidence="ECO:0000259|PROSITE:PS51118"
FT REGION 123..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 101
FT /note="Glucose"
FT /evidence="ECO:0007829|PDB:2F2E"
FT CARBOHYD 102
FT /note="Glucose"
FT /evidence="ECO:0007829|PDB:2F2E"
FT CARBOHYD 113
FT /note="Glucose"
FT /evidence="ECO:0007829|PDB:2F2E"
SQ SEQUENCE 146 AA; 16208 MW; CF71532B1E1B1494 CRC64;
MVKRTSHKQA SCPVARPLDV IGDGWSMLIV RDAFEGLTRF GEFQKSLGLA KNILAARLRN
LVEHGVMVAV PAESGSHQEY RLTDKGRALF PLLVAIRQWG EDYFFAPDES HVRLVERDSG
QPVPRLQVRA GDGSPLAAED TRVSRD
//
