ID Q9J2J2_9GAMA Unreviewed; 304 AA.
AC Q9J2J2;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=ribonucleoside-diphosphate reductase {ECO:0000256|ARBA:ARBA00012274};
DE EC=1.17.4.1 {ECO:0000256|ARBA:ARBA00012274};
GN Name=ORF60 {ECO:0000313|EMBL:AAF60046.1};
OS Rhesus monkey rhadinovirus H26-95.
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Rhadinovirus;
OC Rhadinovirus macacinegamma5; Macacine gammaherpesvirus 5.
OX NCBI_TaxID=69256 {ECO:0000313|EMBL:AAF60046.1, ECO:0000313|Proteomes:UP000162467};
RN [1] {ECO:0000313|EMBL:AAF60046.1, ECO:0000313|Proteomes:UP000162467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Macaca mulatta rhadinovirus isolate 26-95
RC {ECO:0000313|EMBL:AAF60046.1};
RX PubMed=10708456; DOI=10.1128/JVI.74.7.3388-3398.2000;
RA Alexander L., Denekamp L., Knapp A., Auerbach M.R., Damania B.,
RA Desrosiers R.C.;
RT "The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence
RT similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey
RT rhadinovirus isolate 17577.";
RL J. Virol. 74:3388-3398(2000).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the ribonucleoside diphosphate reductase small
CC chain family. {ECO:0000256|ARBA:ARBA00009303}.
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DR EMBL; AF210726; AAF60046.1; -; Genomic_DNA.
DR UniPathway; UPA00326; -.
DR Proteomes; UP000162467; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:UniProtKB-EC.
DR GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd01049; RNRR2; 1.
DR Gene3D; 1.10.620.20; Ribonucleotide Reductase, subunit A; 1.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR012348; RNR-like.
DR InterPro; IPR033909; RNR_small.
DR InterPro; IPR030475; RNR_small_AS.
DR InterPro; IPR000358; RNR_small_fam.
DR PANTHER; PTHR23409; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; 1.
DR PANTHER; PTHR23409:SF18; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2; 1.
DR Pfam; PF00268; Ribonuc_red_sm; 1.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00368; RIBORED_SMALL; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 150..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 304 AA; 34967 MW; 8D4E0A23F27571BF CRC64;
MESPDRFLYA SDHPGFLALT QETWQNRWFP SQISLHEDSD EVRLLSPTDR EFYQFLFTFL
GMAESLVNFN IEDLVKEFSN HDVTHYYAEQ VAMENIHGKV YANILNLFFG GNRGDLMIYA
KKIVEDATLA KKIDWLHSRV RKATTRAEKV LLFLVIEGIY FISSFYSIGL FRLRGIMRGV
CLANDYISRD ELLHTRAASL LYNTMISRDE SPSVAYIHGL FREAVEIETL FIRSKSRDVT
MVNVGDIEQF LQATADRILK SINIPPLFGA RPPNACPLSY TSAKSVNFFE RDNSEYVTSV
HNDL
//
