ID V211_FOWPN Reviewed; 125 AA.
AC Q9J524;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Probable growth factor FPV211;
DE Flags: Precursor;
GN OrderedLocusNames=FPV211;
OS Fowlpox virus (strain NVSL) (FPV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Avipoxvirus; Fowlpox virus.
OX NCBI_TaxID=928301;
OH NCBI_TaxID=7742; Vertebrata.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10729156; DOI=10.1128/jvi.74.8.3815-3831.2000;
RA Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT "The genome of fowlpox virus.";
RL J. Virol. 74:3815-3831(2000).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF198100; AAF44555.1; -; Genomic_DNA.
DR RefSeq; NP_039174.1; NC_002188.1.
DR SMR; Q9J524; -.
DR GeneID; 1486783; -.
DR KEGG; vg:1486783; -.
DR Proteomes; UP000008597; Segment.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR10740:SF14; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10740; TRANSFORMING GROWTH FACTOR ALPHA; 1.
DR PRINTS; PR00009; EGFTGF.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 3: Inferred from homology;
KW Disulfide bond; EGF-like domain; Growth factor; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..48
FT /evidence="ECO:0000255"
FT CHAIN 49..125
FT /note="Probable growth factor FPV211"
FT /id="PRO_0000007606"
FT DOMAIN 80..120
FT /note="EGF-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT DISULFID 84..97
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT DISULFID 92..108
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT DISULFID 110..119
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 125 AA; 14559 MW; A0C676CABCA7EB28 CRC64;
MKEPLIEVKR EYNLIKTLTG KKFVVSTSIV VVLLIINMIF YGIRIHELAV IRRNSETHIS
SFNYKGQAQA QNKRVKNTRL FEKCKSKFNN FCIYGECMNI INLDKKFCIC NKGYTGNRCD
IVSIR
//
