ID Q9KLT5_VIBCH Unreviewed; 323 AA.
AC Q9KLT5;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Fructokinase {ECO:0000313|EMBL:AAF96557.1};
GN OrderedLocusNames=VC_A0656 {ECO:0000313|EMBL:AAF96557.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96557.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF96557.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
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DR EMBL; AE003853; AAF96557.1; -; Genomic_DNA.
DR PIR; A82433; A82433.
DR RefSeq; NP_233045.1; NC_002506.1.
DR AlphaFoldDB; Q9KLT5; -.
DR STRING; 243277.VC_A0656; -.
DR DNASU; 2612581; -.
DR EnsemblBacteria; AAF96557; AAF96557; VC_A0656.
DR KEGG; vch:VC_A0656; -.
DR PATRIC; fig|243277.26.peg.3284; -.
DR eggNOG; COG0524; Bacteria.
DR HOGENOM; CLU_027634_6_1_6; -.
DR Proteomes; UP000000584; Chromosome 2.
DR GO; GO:0008865; F:fructokinase activity; IEA:UniProt.
DR GO; GO:0006000; P:fructose metabolic process; IEA:UniProt.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43085:SF1; KETOHEXOKINASE; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003704};
KW Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 18..314
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 323 AA; 35000 MW; 5673E1B2C3FE0CAD CRC64;
MNALVRLSSN HILRSDSMSR VWLTGDAVVD LIPDGQQHYL KCPGGAPANV AVAIARLCGR
SAFFGRVGND PFGRFMQQTL TDEQVDCQHL YFDPVHRTST VVVDLDEHGE RSFTFMVKPS
ADQFLQLSDI PSFQNGEWLH VCSIALANQP SRSSTFAAIA QMKEVGGYVS FDPNLREEVW
SEPQELQATV MRAVGLADVV KFSEEELQFL TGTQSIEEGL QAIADFQIPL VVVTLGAKGA
LVVTPNSRQI VSGKAVKPID TTGAGDAFVG GLLYRLSVAQ DWHNQATILD AVKWANGCGA
LATTQKGAMT ALPNQAALYA FLE
//
