ID Q9KS52_VIBCH Unreviewed; 200 AA.
AC Q9KS52;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 123.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:AAF94565.1};
GN OrderedLocusNames=VC_1408 {ECO:0000313|EMBL:AAF94565.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF94565.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF94565.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
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DR EMBL; AE003852; AAF94565.1; -; Genomic_DNA.
DR PIR; E82203; E82203.
DR RefSeq; NP_231051.1; NC_002505.1.
DR RefSeq; WP_001264144.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KS52; -.
DR STRING; 243277.VC_1408; -.
DR DNASU; 2614040; -.
DR EnsemblBacteria; AAF94565; AAF94565; VC_1408.
DR GeneID; 66939303; -.
DR KEGG; vch:VC_1408; -.
DR PATRIC; fig|243277.26.peg.1338; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_27_0_6; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR039536; TetR_C_Proteobacteria.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF119; TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF14246; TetR_C_7; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000000584}.
FT DOMAIN 6..66
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 29..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 200 AA; 22608 MW; F14537BC1FEBF7B8 CRC64;
MRVKSEEKRQ AILEIAKDSF TKQGFEQTSM SHIAKMLGGS KATLYNYFSS KEEIFTAVME
SSATEQIALS FLSLDHNREL KPALLEFGYN FLNSVLTQDA MSIYRMAIHE ADRSAIGRHF
YENGPKRGWA RLSRYITCQI ECGSLKECDP WIAAMHFKAL LSAQYFEPFS LGAIEKPTSS
ELKATTQRAV EAFLCLYAAD
//
