ID Q9KTJ3_VIBCH Unreviewed; 316 AA.
AC Q9KTJ3;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE SubName: Full=Trehalose operon repressor {ECO:0000313|EMBL:AAF94071.1};
GN OrderedLocusNames=VC_0909 {ECO:0000313|EMBL:AAF94071.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF94071.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF94071.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
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DR EMBL; AE003852; AAF94071.1; -; Genomic_DNA.
DR PIR; E82266; E82266.
DR RefSeq; NP_230556.1; NC_002505.1.
DR RefSeq; WP_001080438.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KTJ3; -.
DR STRING; 243277.VC_0909; -.
DR DNASU; 2614200; -.
DR EnsemblBacteria; AAF94071; AAF94071; VC_0909.
DR GeneID; 69720384; -.
DR KEGG; vch:VC_0909; -.
DR PATRIC; fig|243277.26.peg.866; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_9_0_6; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01542; PBP1_TreR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR012771; Trehalos_R_gpbac.
DR NCBIfam; TIGR02405; trehalos_R_Ecol; 1.
DR PANTHER; PTHR30146:SF153; HTH-TYPE TRANSCRIPTIONAL REGULATOR TRER; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 316 AA; 34935 MW; 5A56436CCB22F6CE CRC64;
MNRKLTILDI ARLSGVGKST VSRVLTNDPK VKPETRAKVE QVIAESGYVP SKSAQTMRGG
SQKVVGIIIS RLDSPSENKA VSTMLQAFYA HGYDVVIMES QFSREKTNAH LKVLAKRQVD
GVIVFGFTDI DHDALLSWQH RCVLLAMHSD EISSINYDNA GVIERALQHL AQKQLRDIAF
IGVDPRDKTT GEQRLNAYLN WCVEHEIVAN YQTGQLHHES AYLLVDKVLT EQTQAIVCAS
DTLALGVIKR LQELQRDDVV VTGVGGNELL SFLFPNIFSV DPGYREAGKL AADLLIEQLC
GSDHGCVHLT QMPVSR
//
