ID Q9KU69_VIBCH Unreviewed; 175 AA.
AC Q9KU69;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Ubiquinone biosynthesis accessory factor UbiT {ECO:0000256|HAMAP-Rule:MF_02231};
GN Name=ubiT {ECO:0000256|HAMAP-Rule:MF_02231};
GN OrderedLocusNames=VC_0654 {ECO:0000313|EMBL:AAF93820.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF93820.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF93820.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- FUNCTION: Required for O(2)-independent ubiquinone (coenzyme Q)
CC biosynthesis. Likely functions as an accessory factor.
CC {ECO:0000256|HAMAP-Rule:MF_02231}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_02231}.
CC -!- SIMILARITY: Belongs to the UbiT family. {ECO:0000256|HAMAP-
CC Rule:MF_02231}.
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DR EMBL; AE003852; AAF93820.1; -; Genomic_DNA.
DR PIR; A82297; A82297.
DR RefSeq; NP_230303.1; NC_002505.1.
DR RefSeq; WP_000932672.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KU69; -.
DR STRING; 243277.VC_0654; -.
DR DNASU; 2615444; -.
DR EnsemblBacteria; AAF93820; AAF93820; VC_0654.
DR GeneID; 69720590; -.
DR KEGG; vch:VC_0654; -.
DR PATRIC; fig|243277.26.peg.625; -.
DR eggNOG; COG3154; Bacteria.
DR HOGENOM; CLU_111894_1_0_6; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR HAMAP; MF_02231; UbiT; 1.
DR InterPro; IPR039543; POX18/NSL-TP1.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR016830; UbiT.
DR PANTHER; PTHR10094; STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN; 1.
DR PANTHER; PTHR10094:SF32; UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIT; 1.
DR Pfam; PF02036; SCP2; 1.
DR PIRSF; PIRSF025550; UCP025550_lpd_carrier; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW Ubiquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_02231}.
FT DOMAIN 46..134
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
SQ SEQUENCE 175 AA; 19943 MW; FB49A8EB38A5468D CRC64;
MLNKIRTQLV QNAASILRSP IHLLPQNVQK KALLDAMGLV FREALQDGDF EFLEDKWLKV
EVKDMELRWF ISYQNDKLVV ADKPVAEDVS FSGNLNDLVL IAGRKEDPDT LFFQRRLSIE
GDTELGLEVK NLMDSVDLQQ LPKALQILLH QLADFVHKGM QTPNSSHEVI NAYSN
//
