ID Y2324_STRCO Reviewed; 563 AA.
AC Q9KXJ6;
DT 21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 125.
DE RecName: Full=Putative ABC transporter ATP-binding protein SCO2324;
DE EC=7.-.-.-;
GN OrderedLocusNames=SCO2324; ORFNames=SCC53.15;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- FUNCTION: Probably part of an ABC transporter complex. Responsible for
CC energy coupling to the transport system (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AL939112; CAB93444.1; -; Genomic_DNA.
DR RefSeq; NP_626571.1; NC_003888.3.
DR RefSeq; WP_011028281.1; NZ_VNID01000001.1.
DR AlphaFoldDB; Q9KXJ6; -.
DR SMR; Q9KXJ6; -.
DR STRING; 100226.gene:17759922; -.
DR TCDB; 3.A.1.32.1; the atp-binding cassette (abc) superfamily.
DR PaxDb; 100226-SCO2324; -.
DR PATRIC; fig|100226.15.peg.2361; -.
DR eggNOG; COG3845; Bacteria.
DR HOGENOM; CLU_000604_86_7_11; -.
DR InParanoid; Q9KXJ6; -.
DR OrthoDB; 501320at2; -.
DR PhylomeDB; Q9KXJ6; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd03225; ABC_cobalt_CbiO_domain1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43553:SF24; ENERGY-COUPLING FACTOR TRANSPORTER ATP-BINDING PROTEIN ECFA1; 1.
DR PANTHER; PTHR43553; HEAVY METAL TRANSPORTER; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Repeat; Translocase; Transport.
FT CHAIN 1..563
FT /note="Putative ABC transporter ATP-binding protein
FT SCO2324"
FT /id="PRO_0000092092"
FT DOMAIN 2..243
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 317..545
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT REGION 271..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..294
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 36..43
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 349..356
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 563 AA; 59587 MW; FFC8477F9F7FB48F CRC64;
MIRFEDVSVT YDGATEPTVR AVDFEVPEGE LVLLAGPSGV GKSTVLGAVG GLVPHFTGGT
LRGRVTVAGR DTRTHKPREL ADVVGTVGQD PLSHFVTDTV EDELAYGMES LGLPPDVMRR
RVEETLDLLG LSDLRSRPIA TLSGGQQQRV AIGSVLTPHP DVLVLDEPTS ALDPAAAEEV
LAVLQRLVHD LGTTVLMAEH RLERVIQYAD QVVLLPAPGE APLIGAPAEV MAVSPVYPPV
VGLGRLAGWS PLPLTIRNAR RRAAPLRERL AGREIPDHTP PPSAPLPAPP APRPVTSRWR
RRGKRPENPS APTPYAAEVR SLAVRRDRVQ ALRHVDLTVS PGETVALMGR NGAGKSTLLS
ALVGLVEPSA GSVRAGDAVP HRTAPRDLVR RVGLVPQEPR DLLYADTVAA ECAAADRDAD
AAPGTCRALL SELLPGITDD IHPRDLSEGQ RLTLALSVVL TARPPLLLLD EPTRGLDYAA
KARLAGILRG LAAEGHAIVL ATHDVELAAE LAHRVVLLAE GEVIADGPAA DVVVASPSYA
PQVAKVLAPR KWLTVAQVRE ALT
//
