ID Q9KY99_STRCO Unreviewed; 571 AA.
AC Q9KY99;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 135.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN Name=chiA {ECO:0000313|EMBL:CAB92596.1};
GN OrderedLocusNames=SCO5003 {ECO:0000313|EMBL:CAB92596.1};
GN ORFNames=SCK15.05c {ECO:0000313|EMBL:CAB92596.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB92596.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB92596.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
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DR EMBL; AL939122; CAB92596.1; -; Genomic_DNA.
DR RefSeq; NP_629155.1; NC_003888.3.
DR RefSeq; WP_011029996.1; NZ_VNID01000027.1.
DR AlphaFoldDB; Q9KY99; -.
DR STRING; 100226.gene:17762652; -.
DR CAZy; CBM16; Carbohydrate-Binding Module Family 16.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR PaxDb; 100226-SCO5003; -.
DR DNASU; 1100444; -.
DR PATRIC; fig|100226.15.peg.5082; -.
DR eggNOG; COG3469; Bacteria.
DR HOGENOM; CLU_019399_1_1_11; -.
DR InParanoid; Q9KY99; -.
DR OrthoDB; 5172397at2; -.
DR PhylomeDB; Q9KY99; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR CDD; cd02871; GH18_chitinase_D-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR003305; CenC_carb-bd.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR45708; ENDOCHITINASE; 1.
DR PANTHER; PTHR45708:SF49; ENDOCHITINASE; 1.
DR Pfam; PF02018; CBM_4_9; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..571
FT /note="chitinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030176763"
FT DOMAIN 188..270
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 281..566
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 172..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 58102 MW; DCD7AD7BEC5E4F72 CRC64;
MDPVRRRSRG RRLGSLTGAV TAALALAFTA VGPASAADVN NAKNAGFESG LSNWACSANS
GTTVASPAHA GSAALKATPA GQDNARCSQS VAVKPNSTYT LSAWVQGGYS YLGVTGTGTT
DVSTWTPDST AWKQLKTTFS TGSSTTSVSV YTHGWYGQAA YYVDDLSVFG PDGGGGDGGN
PDPTVPSAPA GLSVSGTTPN SASLSWNTVS GATGYNVYRD GTKVTAVTGT SATVTGLAAS
TSYSFQVTAT NAAGESVKSA AVTARTTAPD DGGNGGDLPK HAVTGYWQNF NNGATVQKIS
DVPSAYDIIA VAFADATTTP GAVTFNLDSA GLGGYTVDQF KADVRAKQAA GKKVIISVGG
EKGTVSVNSS ASATNFANSV YSVMREYGFD GVDIDLENGL NPTYMTQALR ALSAKAGPDM
ILTMAPQTID MQSTQGGYFQ TALNVKDILT VVNMQYYNSG TMLGCDGKVY AQGTVDFLTA
LACIQLEGGL APSQVGLGLP ASTRAAGGGY VSPSVVNAAL DCLTKATNCG SFKPSKTYPD
LRGAMTWSTN WDATAGNAWS NSVGAHVHAL P
//
