ID Q9KYY6_STRCO Unreviewed; 424 AA.
AC Q9KYY6;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Crp-family transcriptional regulator {ECO:0000313|EMBL:CAB90901.1};
GN OrderedLocusNames=SCO7543 {ECO:0000313|EMBL:CAB90901.1};
GN ORFNames=SC8G12.19 {ECO:0000313|EMBL:CAB90901.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB90901.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB90901.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; AL939132; CAB90901.1; -; Genomic_DNA.
DR RefSeq; NP_631587.1; NC_003888.3.
DR AlphaFoldDB; Q9KYY6; -.
DR STRING; 100226.gene:17765203; -.
DR PaxDb; 100226-SCO7543; -.
DR PATRIC; fig|100226.15.peg.7657; -.
DR eggNOG; COG1522; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_3_11; -.
DR InParanoid; Q9KYY6; -.
DR OrthoDB; 3189808at2; -.
DR PhylomeDB; Q9KYY6; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IMP:CACAO.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT REGION 403..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 43886 MW; 78BF0E41BEDDC4C4 CRC64;
MTGMQMPSGV HALVRRTHEE RVMRALQENG AMSRGEIARV VGLSRTTLSE ITGNLLQRGA
IVVVDTDASR REGSGRPAER LALDPASAQF MGVDFGHRRV HVVVADAAHE IMVSGSVRYE
DTATWPTRTE RALELVDRLS GEAGVHYGAL QGIGIGVPGP YPAPEGAAWP RATPGTTVLR
PAPEGVDVAF AERFDAPVIV DNNTRLAALA EAISGADSVA DLVYVRLSDG VGGGLVVGGQ
LVTGSSGLAG ELGHVTVEPA GRPCRCGKRG CLETVASVPG ILAACWEFGL RLENLDDLAA
AVRRAHPVVD RVLREAAGAL GRVVGAATMM LNPAKVVIGG EITRLAPVLV EQVAATLAAE
IFPTASAGPV VAAARLSDDD GAIGALAAVF HSSPLLARYP ETADVKGRSD APHSATEGAA
HVRP
//
