ID Q9L009_STRCO Unreviewed; 333 AA.
AC Q9L009;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:CAB88182.1};
GN OrderedLocusNames=SCO2304 {ECO:0000313|EMBL:CAB88182.1};
GN ORFNames=SCC30.12c {ECO:0000313|EMBL:CAB88182.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB88182.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB88182.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; AL939112; CAB88182.1; -; Genomic_DNA.
DR RefSeq; NP_626552.1; NC_003888.3.
DR AlphaFoldDB; Q9L009; -.
DR STRING; 100226.gene:17759902; -.
DR PaxDb; 100226-SCO2304; -.
DR PATRIC; fig|100226.15.peg.2341; -.
DR eggNOG; COG2030; Bacteria.
DR HOGENOM; CLU_040078_1_1_11; -.
DR InParanoid; Q9L009; -.
DR OrthoDB; 5522043at2; -.
DR PhylomeDB; Q9L009; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0044594; F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity; IBA:GO_Central.
DR GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IBA:GO_Central.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IBA:GO_Central.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR CDD; cd03448; HDE_HSD; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR039569; MaoC-like_dehydrat_N.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR13078:SF56; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2; 1.
DR PANTHER; PTHR13078; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED; 1.
DR Pfam; PF13452; MaoC_dehydrat_N; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 86..168
FT /note="N-terminal of MaoC-like dehydratase"
FT /evidence="ECO:0000259|Pfam:PF13452"
FT DOMAIN 198..298
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
FT REGION 182..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 35241 MW; FE07C1CC04BF612D CRC64;
MRLSGVGDDK CHGRPASRTV GVSVIVVVSG RSRRAMPVDA AGALAAAPRV REIAWDHKDV
QLYHLGIGAG RPATDPRELR YTLESRLHVL PSFATVAGGG APGVIGTLSA PGVDVDLARV
LHGGQRLRLH RPVPVRGRAS AASRVVAVYD KGTAAVLVLR TEVTDADGPL WTDEAEVFVR
GEGGWGGERG PSGRPSPPPA DPPDQIVDRA VREDQALLYR LSGDWNPLHA DPEFAARAGF
ERPVLHGLCT YGATLKAVVD TLLDGDVTRV RDYRTRFAGV VYPGETLRVR MWRTAGTGGA
GAGGARTGEA RVAVNAVERD DAPVLADTVV RYG
//
