ID Q9LHN3_ARATH Unreviewed; 760 AA.
AC Q9LHN3;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 166.
DE SubName: Full=AT3g18860/MCB22_3 {ECO:0000313|EMBL:AAK95297.1};
DE SubName: Full=Transducin family protein / WD-40 repeat family protein {ECO:0000313|EMBL:AEE76160.1};
GN OrderedLocusNames=At3g18860 {ECO:0000313|Araport:AT3G18860,
GN ECO:0000313|EMBL:AEE76160.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:BAB03095.1};
RN [1] {ECO:0000313|EMBL:BAB03095.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Nakamura Y.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2] {ECO:0000313|EMBL:AEE76160.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130713; DOI=10.1038/35048706;
RG European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG Institute for Genomic Research;
RG Kazusa DNA Research Institute;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3] {ECO:0000313|EMBL:AAK95297.1}
RP NUCLEOTIDE SEQUENCE.
RA Cheuk R., Chen H., Kim C.J., Koesema E., Meyers M.C., Banh J., Bowser L.,
RA Carninci P., Dale J.M., Goldsmith A.D., Hayashizaki Y., Ishida J.,
RA Jiang P.X., Jones T., Kamiya A., Karlin-Neumann G., Kawai J., Lam B.,
RA Lee J.M., Lin J., Liu S.X., Miranda M., Narusaka M., Nguyen M.,
RA Onodera C.S., Palm C.J., Pham P.K., Quach H.L., Sakurai T., Satou M.,
RA Seki M., Southwick A., Tang C.C., Toriumi M., Yamada K., Yamamura Y.,
RA Yu G., Yu S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AEE76160.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AEE76160.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AF410311; AAK95297.1; -; mRNA.
DR EMBL; CP002686; AEE76160.1; -; Genomic_DNA.
DR EMBL; AP002039; BAB03095.1; -; Genomic_DNA.
DR RefSeq; NP_566620.1; NM_112772.3.
DR AlphaFoldDB; Q9LHN3; -.
DR SMR; Q9LHN3; -.
DR IntAct; Q9LHN3; 1.
DR STRING; 3702.Q9LHN3; -.
DR PaxDb; 3702-AT3G18860-1; -.
DR ProteomicsDB; 177559; -.
DR EnsemblPlants; AT3G18860.1; AT3G18860.1; AT3G18860.
DR GeneID; 821419; -.
DR Gramene; AT3G18860.1; AT3G18860.1; AT3G18860.
DR KEGG; ath:AT3G18860; -.
DR Araport; AT3G18860; -.
DR TAIR; AT3G18860; -.
DR eggNOG; KOG0301; Eukaryota.
DR HOGENOM; CLU_011791_2_0_1; -.
DR OMA; RTFDTCD; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LHN3; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.10.20.870; PFU (PLAA family ubiquitin binding), C-terminal domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015155; PFU.
DR InterPro; IPR038122; PFU_sf.
DR InterPro; IPR013535; PUL_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR19849:SF0; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR Pfam; PF09070; PFU; 1.
DR Pfam; PF08324; PUL; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51394; PFU; 1.
DR PROSITE; PS51396; PUL; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q9LHN3,
KW ECO:0007829|ProteomicsDB:Q9LHN3};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 16..56
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 62..108
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 109..138
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 147..187
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 186..216
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 226..257
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 361..457
FT /note="PFU"
FT /evidence="ECO:0000259|PROSITE:PS51394"
FT DOMAIN 486..757
FT /note="PUL"
FT /evidence="ECO:0000259|PROSITE:PS51396"
SQ SEQUENCE 760 AA; 84274 MW; 645D412206410105 CRC64;
MVMDIDFNEY KLRCELHGHD DDVRGICVCN DENIATSSRD RTIRVWSLDP SDKRKYTSEK
ILLGHTSFVG PLAWIPPTDE YPEGRLVSGS MDTFVFVWNL MNGENIQTLK GHQMQVTGVA
IDNEDIVSSS VDQTLKRWRN GQLVESWDAH QSPIQAVIRL PSGELVSGSS DASLKLWKGK
TSLQTLSGHT DTVRGLAVMP DLGFLSASHD GSIRLWALSG EVLLEMVGHT SLVYSVDAHS
SGLIVSASED RHAKIWKDGV CVQSLEHPGC IWDAKFLETG DIVTACSDGV VRVWTVRHDA
IADQMEIDAY DSQISQYKLS RKKVGGLKLD ELPGLDSLTS PGTSDGQTKV VREGDNGVAY
AWNMKEQRWD KIGEVVDGPD GVADRPIHEG VQYDFVFDVD IGDGEPIRKL PYNRSDNPYD
AADKWLLKEN LPFAYRQQIV EFILQNSGQK DFNFNPSFRD PFTGANAYVP GQASRTAATP
AKPLYKHIPK RGVLVFDAAQ YDGILKKMTE FNTTLRSDAV NNDKSLTELE VSRVGAIVNI
LKDTSHYHST NFADMDIALL LKVLQAWPPA MMFPATDIVR MLVLHHHGAS LLIKHVENNN
DLLLDLIKKV TEDSALPANL LTTVRVLVNL FKNSSFHYWL QTHHSQILDA FSNCYSSPNK
NLQLAYSTLL LNYAVLLIEK KDQEGQAQVL SAALQVAEEE AADVDSKFRS LVAIGSLMLE
GLVKKIAIDF DVESIAKSAK ASKEAKIAEV GADIDLVIRQ
//
