ID C71BP_ARATH Reviewed; 501 AA.
AC Q9LTL2; Q1PEL4;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 139.
DE RecName: Full=Cytochrome P450 71B25;
DE EC=1.14.-.-;
GN Name=CYP71B25; OrderedLocusNames=At3g26270; ORFNames=MTC11.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AB024038; BAB02450.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77140.1; -; Genomic_DNA.
DR EMBL; DQ446703; ABE65971.1; -; mRNA.
DR RefSeq; NP_189258.1; NM_113534.1.
DR AlphaFoldDB; Q9LTL2; -.
DR SMR; Q9LTL2; -.
DR STRING; 3702.Q9LTL2; -.
DR PaxDb; 3702-AT3G26270-1; -.
DR EnsemblPlants; AT3G26270.1; AT3G26270.1; AT3G26270.
DR GeneID; 822230; -.
DR Gramene; AT3G26270.1; AT3G26270.1; AT3G26270.
DR KEGG; ath:AT3G26270; -.
DR Araport; AT3G26270; -.
DR TAIR; AT3G26270; CYP71B25.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_4_1_1; -.
DR InParanoid; Q9LTL2; -.
DR OMA; RFINCPV; -.
DR OrthoDB; 679703at2759; -.
DR PhylomeDB; Q9LTL2; -.
DR BioCyc; ARA:AT3G26270-MONOMER; -.
DR PRO; PR:Q9LTL2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LTL2; baseline and differential.
DR Genevisible; Q9LTL2; AT.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11072; CYP71-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR47956; CYTOCHROME P450 71B11-RELATED; 1.
DR PANTHER; PTHR47956:SF5; CYTOCHROME P450 71B25-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..501
FT /note="Cytochrome P450 71B25"
FT /id="PRO_0000052102"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 445
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 501 AA; 57535 MW; A9C880F285C9E4D9 CRC64;
MAILQSFLLL LSLPFLFTLI YTKKMKESKR NLPPGPAKLP IVGNLHQLQG MVHRCLHELS
KKHGPVMHLQ LGFVPLVLIS SSEAAEEALK THDIECCTRP NTNAARVFSR NNKNIGLGAY
SDEWRELRKV AVREYFSVKK VQSFRYVREE ENHLMVKKLR DLALKQSPVD LSKTLFCLAA
STVFRPVFGQ SFSDNKHFSE EKIEELVFEA QKSLTFKFSD LFPIPGLGWF IGFVSGQHKG
LHKVFIEVDN FLNHMIDDHQ KQNQPQDRSD IVGSLLDMIH NQEQDKSFKL TIDHLKGITQ
DIFLAGIDTS AITMIWAMAE LVNNPRVMKK VQDEIRSCIG IKKERIEEED VGKLQYLKLV
IKETLRLHPA APLLLPRETM ADIKIQGYDI PRKTLLLVSA WSLGRDPKYW KNPEEFNPER
FIDCPVDYKG HSFEFLPFGS GRRFCPGMAS AIATIELTLL NLLYFFDWKL PEEMKDMNME
ESGDVTIVKK VPLELLPVLY H
//
