ID Q9MZT0_BOVIN Unreviewed; 349 AA.
AC Q9MZT0; F1MZ15;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 157.
DE SubName: Full=Fc fragment of IgG receptor Ia {ECO:0000313|Ensembl:ENSBTAP00000067329.1};
DE SubName: Full=Fc gamma receptor I {ECO:0000313|EMBL:AAF80477.1};
GN Name=FCGR1A {ECO:0000313|Ensembl:ENSBTAP00000067329.1,
GN ECO:0000313|VGNC:VGNC:112681};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAF80477.1};
RN [1] {ECO:0000313|EMBL:AAF80477.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10889306; DOI=10.1016/S0165-2427(00)00197-5;
RA Yan Y., Li X., Wang A., Zhang G.;
RT "Molecular cloning and identification of full-length cDNA encoding high
RT affinity Fc receptor for bovine IgG (Fc gamma RI).";
RL Vet. Immunol. Immunopathol. 75:151-159(2000).
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000067329.1, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067329.1,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000067329.1}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000067329.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AF162866; AAF80477.1; -; mRNA.
DR RefSeq; NP_776963.1; NM_174538.2.
DR PaxDb; 9913-ENSBTAP00000011333; -.
DR Ensembl; ENSBTAT00000073891.1; ENSBTAP00000067329.1; ENSBTAG00000008592.6.
DR GeneID; 282227; -.
DR KEGG; bta:282227; -.
DR CTD; 2209; -.
DR VEuPathDB; HostDB:ENSBTAG00000008592; -.
DR VGNC; VGNC:112681; FCGR1A.
DR eggNOG; ENOG502S1XR; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR HOGENOM; CLU_023383_3_0_1; -.
DR OMA; VWFHILF; -.
DR TreeFam; TF335097; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000008592; Expressed in milk and 101 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019771; F:high-affinity IgG receptor activity; IEA:Ensembl.
DR GO; GO:0001788; P:antibody-dependent cellular cytotoxicity; IEA:Ensembl.
DR CDD; cd05752; Ig1_FcgammaR_like; 1.
DR CDD; cd05753; Ig2_FcgammaR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11481:SF11; HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:AAF80477.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..349
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015099922"
FT TRANSMEM 289..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..86
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 95..184
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 349 AA; 39608 MW; D0B77B2EF9408C02 CRC64;
MWLIIALILG APVAEQVDPT KAVITLKPPW VSVFQEENVT LLCEGPHRPG DTATQWFLNG
TAIKTLAPRY SINSATFDDS GEYKCQTGLS MLSDPVQLEI HSDWLLLQVT SRVFTEGDPL
ALRCHAWKNM PVYKMLFYKD GKPFRFSSQD SEFTILQTNL SHNGIYHCSG ERRRRYTSAG
VSITIKELFP APVLRTSFSS PHQEGNLVNL SCETKLPSEK PGQQLYFSFY VGNKTLISRT
TSSEYQTFIA KKEDRRLYWC EAATGDGNLI KRSPELELPV LGLQSTTPVW FHFLFYLAVG
IMFLVDSVLC IVIHKELQRK KMWNLEIYLD SLDSGHGKEV PPTFKNIDN
//
