ID Q9N4U0_CAEEL Unreviewed; 332 AA.
AC Q9N4U0;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2004, sequence version 2.
DT 24-JAN-2024, entry version 153.
DE SubName: Full=Cyclin-H {ECO:0000313|EMBL:CCD64712.1};
GN Name=cyh-1 {ECO:0000313|EMBL:CCD64712.1,
GN ECO:0000313|WormBase:Y49F6B.1};
GN ORFNames=CELE_Y49F6B.1 {ECO:0000313|EMBL:CCD64712.1}, Y49F6B.1
GN {ECO:0000313|WormBase:Y49F6B.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD64712.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD64712.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD64712.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin C subfamily.
CC {ECO:0000256|ARBA:ARBA00008638}.
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DR EMBL; BX284602; CCD64712.1; -; Genomic_DNA.
DR RefSeq; NP_494564.2; NM_062163.4.
DR AlphaFoldDB; Q9N4U0; -.
DR SMR; Q9N4U0; -.
DR STRING; 6239.Y49F6B.1.1; -.
DR EPD; Q9N4U0; -.
DR PaxDb; 6239-Y49F6B-1; -.
DR PeptideAtlas; Q9N4U0; -.
DR EnsemblMetazoa; Y49F6B.1a.1; Y49F6B.1a.1; WBGene00021714.
DR GeneID; 190078; -.
DR UCSC; Y49F6B.1; c. elegans.
DR AGR; WB:WBGene00021714; -.
DR WormBase; Y49F6B.1; CE36037; WBGene00021714; cyh-1.
DR eggNOG; KOG2496; Eukaryota.
DR GeneTree; ENSGT00940000168613; -.
DR HOGENOM; CLU_022620_2_0_1; -.
DR OMA; PHANDFF; -.
DR OrthoDB; 5481790at2759; -.
DR PhylomeDB; Q9N4U0; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00021714; Expressed in embryo and 4 other cell types or tissues.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20524; CYCLIN_CCNH_rpt1; 1.
DR CDD; cd20525; CYCLIN_CCNH_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR031658; Cyclin_C_2.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF8; CYCLIN-H; 1.
DR Pfam; PF16899; Cyclin_C_2; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|EPD:Q9N4U0,
KW ECO:0007829|PeptideAtlas:Q9N4U0};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 75..155
FT /note="Cyclin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00134"
FT DOMAIN 159..267
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16899"
FT REGION 313..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 253..295
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 332 AA; 39037 MW; FA60645DE57D07C3 CRC64;
MYATSTQKRE WTYTPEKLAA MRLEINIKFR QKYESVMQPD ELELFVTPEE ELRMQRSIED
AALKFADKFR PHIWPSVKWT ALAFFKRAFL VWVPSDTSIR MVMMACFYLA MKIDEFYITI
EDFVKNMNVG EPRQNAERIL KLEPELMKIL DYNLTVHCPY RPYEGHLMDM KTRMLLLNFD
LESIRRDSMR FFQNALQTDV LLLYPPSQIA LAAINFGLHA QGKSDEILRE FLRKLIGIEE
DSWAHRDARP EDLEKLEKTV TRVNQIMREV DRNFVAVTEQ ERENHKSQLA RIQALIPALD
ERRKEQWLAG GGVGLMPGEL AEQPVDSDDE IN
//
