ID Q9PX24_MYXVL Unreviewed; 263 AA.
AC Q9PX24;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=M-T7 {ECO:0000313|EMBL:AAF14894.1};
DE SubName: Full=M7 {ECO:0000313|EMBL:AAF15053.1};
GN Name=m007L {ECO:0000313|EMBL:AAF15053.1};
GN Synonyms=m007R {ECO:0000313|EMBL:AAF14894.1};
OS Myxoma virus (strain Lausanne) (MYXV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Leporipoxvirus; Myxoma virus.
OX NCBI_TaxID=31530 {ECO:0000313|Proteomes:UP000000867};
OH NCBI_TaxID=9986; Oryctolagus cuniculus (Rabbit).
RN [1] {ECO:0000313|EMBL:AAF15053.1, ECO:0000313|Proteomes:UP000000867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lausanne {ECO:0000313|EMBL:AAF15053.1,
RC ECO:0000313|Proteomes:UP000000867};
RX PubMed=10562494; DOI=10.1006/viro.1999.0001;
RA Cameron C., Hota-Mitchell S., Chen L., Barrett J., Cao J.X., Macaulay C.,
RA Willer D., Evans D., McFadden G.;
RT "The complete DNA sequence of myxoma virus.";
RL Virology 264:298-318(1999).
RN [2] {ECO:0000313|EMBL:AAF15053.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Lausanne {ECO:0000313|EMBL:AAF15053.1};
RA Cameron C., Hota-Mitchell S., Chen L., Barrett J., Cao J.-X., Macaulay C.,
RA Willer D., Evans D., McFadden G.;
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAF15053.1, ECO:0000313|Proteomes:UP000000867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lausanne {ECO:0000313|EMBL:AAF15053.1,
RC ECO:0000313|Proteomes:UP000000867};
RX PubMed=16356857; DOI=10.1016/j.immuni.2005.10.003;
RA Johnston J.B., Barrett J.W., Nazarian S.H., Goodwin M., Ricuttio D.,
RA Wang G., McFadden G.;
RT "A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit
RT host inflammatory and apoptotic responses to infection.";
RL Immunity 23:587-598(2005).
CC -!- SIMILARITY: Belongs to the type II cytokine receptor family.
CC {ECO:0000256|ARBA:ARBA00005399}.
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DR EMBL; AF170726; AAF14894.1; -; Genomic_DNA.
DR EMBL; AF170726; AAF15053.1; -; Genomic_DNA.
DR RefSeq; NP_051720.1; NC_001132.2.
DR RefSeq; NP_051872.1; NC_001132.2.
DR SMR; Q9PX24; -.
DR GeneID; 932081; -.
DR GeneID; 932170; -.
DR KEGG; vg:932081; -.
DR KEGG; vg:932170; -.
DR Proteomes; UP000000867; Segment.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR GO; GO:0060333; P:type II interferon-mediated signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR021126; IFN_gamma_rc_D2_pox/mammal.
DR InterPro; IPR013783; Ig-like_fold.
DR Pfam; PF07140; IFNGR1_D2; 1.
DR Pfam; PF20634; IFNGR1_transm; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000867}.
FT DOMAIN 104..205
FT /note="Interferon gamma receptor D2"
FT /evidence="ECO:0000259|Pfam:PF07140"
SQ SEQUENCE 263 AA; 29966 MW; 6E8DC2628048754A CRC64;
MDGRLVFLLA SLAIVSDAVR LTSYDLNTFV TWQDDGYTYN VSIKPYTTAT WINVCEWASS
SCNVSLALQY DLDVVSWARL TRVGKYTEYS LEPTCAVARF SPPEVQLVRT GTSVEVLVRH
PVVYLRGQEV SVYGHSFCDY DFGYKTIFLF SKNKRAEYVV PGRYCDNVEC RFSIDSQESV
CATAVLTYGD SYRSEAGVEV CVPELAKREV SPYIVKKSSD LEYVKRAIHN EYRLDTSSEG
RRLEELYLTV ASMFERLVED VFE
//
