GenomeNet

Database: UniProt
Entry: Q9Q8Q7_MYXVL
LinkDB: Q9Q8Q7_MYXVL
Original site: Q9Q8Q7_MYXVL 
ID   Q9Q8Q7_MYXVL            Unreviewed;        74 AA.
AC   Q9Q8Q7;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   12-AUG-2020, entry version 51.
DE   SubName: Full=M39L {ECO:0000313|EMBL:AAF14927.1};
GN   Name=m039L {ECO:0000313|EMBL:AAF14927.1};
OS   Myxoma virus (strain Lausanne) (MYXV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Leporipoxvirus.
OX   NCBI_TaxID=31530 {ECO:0000313|Proteomes:UP000000867};
OH   NCBI_TaxID=9986; Oryctolagus cuniculus (Rabbit).
RN   [1] {ECO:0000313|EMBL:AAF14927.1, ECO:0000313|Proteomes:UP000000867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lausanne {ECO:0000313|EMBL:AAF14927.1,
RC   ECO:0000313|Proteomes:UP000000867};
RX   PubMed=10562494; DOI=10.1006/viro.1999.0001;
RA   Cameron C., Hota-Mitchell S., Chen L., Barrett J., Cao J.X., Macaulay C.,
RA   Willer D., Evans D., McFadden G.;
RT   "The complete DNA sequence of myxoma virus.";
RL   Virology 264:298-318(1999).
RN   [2] {ECO:0000313|EMBL:AAF14927.1, ECO:0000313|Proteomes:UP000000867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lausanne {ECO:0000313|EMBL:AAF14927.1,
RC   ECO:0000313|Proteomes:UP000000867};
RX   PubMed=16356857; DOI=10.1016/j.immuni.2005.10.003;
RA   Johnston J.B., Barrett J.W., Nazarian S.H., Goodwin M., Ricuttio D.,
RA   Wang G., McFadden G.;
RT   "A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit
RT   host inflammatory and apoptotic responses to infection.";
RL   Immunity 23:587-598(2005).
CC   -!- FUNCTION: Late protein which probably plays a role in virus entry into
CC       the host cell. {ECO:0000256|ARBA:ARBA00004101}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Virion membrane
CC       {ECO:0000256|ARBA:ARBA00004381}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004381}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I2 family.
CC       {ECO:0000256|ARBA:ARBA00007048}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF170726; AAF14927.1; -; Genomic_DNA.
DR   RefSeq; NP_051753.1; NC_001132.2.
DR   GeneID; 932115; -.
DR   KEGG; vg:932115; -.
DR   Proteomes; UP000000867; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009175; Poxvirus_I2.
DR   Pfam; PF12575; Pox_EPC_I2-L1; 1.
DR   PIRSF; PIRSF003766; VAC_I2L; 1.
PE   3: Inferred from homology;
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000867};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW   Virion {ECO:0000256|ARBA:ARBA00022844};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00022595}.
FT   TRANSMEM        47..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   74 AA;  8508 MW;  22A02E3A5FD587C2 CRC64;
     MDKLYTALFG VFMTSTDDDF NNFIEVVKSV LTDKPSYMPG ISKGTTWWLV IIAVAVVMCL
     VFFLMMYLKA IRRN
//
DBGET integrated database retrieval system