ID Q9RD71_STRCO Unreviewed; 341 AA.
AC Q9RD71;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=LacI-family transcriptional regulatory protein {ECO:0000313|EMBL:CAB66206.1};
GN OrderedLocusNames=SCO0806 {ECO:0000313|EMBL:CAB66206.1};
GN ORFNames=SCF43.17c {ECO:0000313|EMBL:CAB66206.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB66206.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB66206.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL939106; CAB66206.1; -; Genomic_DNA.
DR RefSeq; NP_625107.1; NC_003888.3.
DR RefSeq; WP_003978054.1; NZ_VNID01000004.1.
DR AlphaFoldDB; Q9RD71; -.
DR STRING; 100226.gene:17758389; -.
DR PaxDb; 100226-SCO0806; -.
DR PATRIC; fig|100226.15.peg.798; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR InParanoid; Q9RD71; -.
DR OrthoDB; 37081at2; -.
DR PhylomeDB; Q9RD71; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 341 AA; 35935 MW; 1C09814979709EDA CRC64;
MAHSVGIKDV ARAAGVSVGT VSNVINRPDT VATETRARVL SAIDRLGYVR SESARQLRAG
RSRIMGLLVL DMGNPFFVDV ARGAERAARE AGLGVMVCNS AQNPGEEAEY LSLFAEQRVR
GVLLTPADAT GRNIEGFRRH NIPFVLVDRV AEGTTECSVS VDDVAGGALA VRHLVDAGHR
SIAYVSGPPG LNQVRDRRTG ALAALAEAGL GPDALRELPT ERLDVAAGRD AGARLLGLAE
RPTAVFCAND LLALGVLQAM YAAGVGVPDD LAIVGYDDIE FAAAAAVPLT SVRQPAVTMG
AMAAELLLEE TELEGTDRTH PHRRVVLQPE LVVRRSSLAA R
//
