ID Q9RVD9_DEIRA Unreviewed; 356 AA.
AC Q9RVD9;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=GGDEF family protein {ECO:0000313|EMBL:AAF10664.1};
GN OrderedLocusNames=DR_1090 {ECO:0000313|EMBL:AAF10664.1};
OS Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG
OS 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1).
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=243230 {ECO:0000313|EMBL:AAF10664.1, ECO:0000313|Proteomes:UP000002524};
RN [1] {ECO:0000313|EMBL:AAF10664.1, ECO:0000313|Proteomes:UP000002524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 /
RC NCIMB 9279 / R1 / VKM B-1422 {ECO:0000313|Proteomes:UP000002524};
RX PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA Vamathevan J.J., Lam P., McDonald L., Utterback T., Zalewski C.,
RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA Ketchum K.A., Nelson K.E., Salzberg S., Smith H.O., Venter J.C.,
RA Fraser C.M.;
RT "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT R1.";
RL Science 286:1571-1577(1999).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE000513; AAF10664.1; -; Genomic_DNA.
DR PIR; B75438; B75438.
DR RefSeq; NP_294814.1; NC_001263.1.
DR RefSeq; WP_010887733.1; NZ_JMLF01000002.1.
DR AlphaFoldDB; Q9RVD9; -.
DR STRING; 243230.DR_1090; -.
DR PaxDb; 243230-DR_1090; -.
DR EnsemblBacteria; AAF10664; AAF10664; DR_1090.
DR GeneID; 69517336; -.
DR KEGG; dra:DR_1090; -.
DR PATRIC; fig|243230.17.peg.1286; -.
DR eggNOG; COG2199; Bacteria.
DR HOGENOM; CLU_000445_11_1_0; -.
DR InParanoid; Q9RVD9; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000002524; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0052621; F:diguanylate cyclase activity; IBA:GO_Central.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002524};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 220..350
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 356 AA; 39287 MW; E1C8F10A0680F2FF CRC64;
MLLTLIINFC LLTTMMYLLS LTYKSAEDIT ATAIHVPRLL LLAVMAVVLM LYPAEVAPGV
IIDMRAVPIA YLALRKGVWA GLLALIPLLL YRFHLGGVGT WSAVFSAVGV VLLGGLLHRS
VDLSAPRLDW RSLWWRLLLV FMPNGILIPV LRGDPAALLT VYLPLLVVTY AGFLVSLGIQ
RNRYRLLSLI ATYEQQAHQD ALSDLPNRRQ FDLDFVRMDV GDLLCLVDID HFKKINDTYG
HAAGDEVLTQ LGGVLKGRLR SHDQAYRYGG EEFAVIFRSP GNAAPELLAE RLRQAVEHTS
FTALAGHPLT VSIGVTRRGA APLDTCFLEA DQALYAAKTA GRNQVRVWPL EQPPEA
//
