ID Q9S218_STRCO Unreviewed; 271 AA.
AC Q9S218;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:CAB52846.1};
GN OrderedLocusNames=SCO1782 {ECO:0000313|EMBL:CAB52846.1};
GN ORFNames=SCI51.22c {ECO:0000313|EMBL:CAB52846.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB52846.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB52846.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
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DR EMBL; AL939110; CAB52846.1; -; Genomic_DNA.
DR PIR; T36885; T36885.
DR RefSeq; NP_626053.1; NC_003888.3.
DR RefSeq; WP_011027974.1; NZ_VNID01000018.1.
DR AlphaFoldDB; Q9S218; -.
DR STRING; 100226.gene:17759376; -.
DR TCDB; 1.C.109.1.2; the bacterial hemolysin a (tlya) family.
DR PaxDb; 100226-SCO1782; -.
DR PATRIC; fig|100226.15.peg.1801; -.
DR eggNOG; COG1189; Bacteria.
DR HOGENOM; CLU_058015_2_0_11; -.
DR InParanoid; Q9S218; -.
DR OrthoDB; 9784736at2; -.
DR PhylomeDB; Q9S218; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 7..74
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 271 AA; 28455 MW; 87D3A01DB831BEDF CRC64;
MAGVARRRLD AELVRRKLAR SREHASQLIA AGRVTVGKTV ATKPATQVET AAAIVVTADD
NDPDYVSRGG HKLAGALAAF VPHGLVVEGR RALDAGASTG GFTDVLLRAG AAHVVAVDVG
YGQLAWSLRQ DERVTVKDRT NVRELTPEAI DGEPVDLVVG DLSFIPLALV LPALVRCTRP
GADLVMMVKP QFEVGKERLG SGGVVRSAQL RAEAVRGVAR KAWELGLGVK GVTASPLPGP
SGNVEYFLWL RAGAGELDPA DVDRAVAEGP R
//
