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Database: UniProt
Entry: Q9SDG8
LinkDB: Q9SDG8
Original site: Q9SDG8 
ID   AGO4A_ORYSJ             Reviewed;         904 AA.
AC   Q9SDG8; A0A0P0V0X4;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   16-OCT-2019, entry version 98.
DE   RecName: Full=Protein argonaute 4A;
DE            Short=OsAGO4a;
GN   Name=AGO4A; OrderedLocusNames=Os01g0275600, LOC_Os01g16870;
GN   ORFNames=P0038F12.13;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M.,
RA   Okamoto M., Ando T., Aoki H., Arita K., Hamada M., Harada C.,
RA   Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M.,
RA   Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K.,
RA   Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I.,
RA   Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y.,
RA   Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M.,
RA   Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M.,
RA   Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K.,
RA   Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K.,
RA   Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y.,
RA   Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H.,
RA   McCombie W.R., Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S.,
RA   Childs K.L., Davidson R.M., Lin H., Quesada-Ocampo L.,
RA   Vaillancourt B., Sakai H., Lee S.S., Kim J., Numa H., Itoh T.,
RA   Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using
RT   next generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18826656; DOI=10.1186/1471-2164-9-451;
RA   Kapoor M., Arora R., Lama T., Nijhawan A., Khurana J.P., Tyagi A.K.,
RA   Kapoor S.;
RT   "Genome-wide identification, organization and phylogenetic analysis of
RT   dicer-like, argonaute and RNA-dependent RNA polymerase gene families
RT   and their expression analysis during reproductive development and
RT   stress in rice.";
RL   BMC Genomics 9:451-451(2008).
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway. May bind
CC       to short RNAs such as microRNAs (miRNAs) or short interfering RNAs
CC       (siRNAs), and represses the translation of mRNAs which are
CC       complementary to them (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the argonaute family. Ago subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AK064813; Type=Frameshift; Evidence={ECO:0000305};
DR   EMBL; AP000836; BAA88176.1; -; Genomic_DNA.
DR   EMBL; AP008207; BAF04636.1; -; Genomic_DNA.
DR   EMBL; AP014957; BAS71541.1; -; Genomic_DNA.
DR   EMBL; AK064813; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015621073.1; XM_015765587.1.
DR   RefSeq; XP_015621074.1; XM_015765588.1.
DR   SMR; Q9SDG8; -.
DR   STRING; 4530.OS01T0275600-01; -.
DR   iPTMnet; Q9SDG8; -.
DR   PaxDb; Q9SDG8; -.
DR   PRIDE; Q9SDG8; -.
DR   EnsemblPlants; Os01t0275600-01; Os01t0275600-01; Os01g0275600.
DR   GeneID; 4324438; -.
DR   Gramene; Os01t0275600-01; Os01t0275600-01; Os01g0275600.
DR   KEGG; osa:4324438; -.
DR   eggNOG; KOG1041; Eukaryota.
DR   eggNOG; ENOG410XP07; LUCA.
DR   InParanoid; Q9SDG8; -.
DR   KO; K11593; -.
DR   OMA; CYEQMFT; -.
DR   OrthoDB; 159407at2759; -.
DR   Proteomes; UP000059680; Chromosome 1.
DR   ExpressionAtlas; Q9SDG8; baseline and differential.
DR   Genevisible; Q9SDG8; OS.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR014811; ArgoL1.
DR   InterPro; IPR032472; ArgoL2.
DR   InterPro; IPR032474; Argonaute_N.
DR   InterPro; IPR003100; PAZ_dom.
DR   InterPro; IPR036085; PAZ_dom_sf.
DR   InterPro; IPR003165; Piwi.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF08699; ArgoL1; 1.
DR   Pfam; PF16488; ArgoL2; 1.
DR   Pfam; PF16486; ArgoN; 1.
DR   Pfam; PF02170; PAZ; 1.
DR   Pfam; PF02171; Piwi; 1.
DR   SMART; SM01163; DUF1785; 1.
DR   SMART; SM00950; Piwi; 1.
DR   SUPFAM; SSF101690; SSF101690; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50821; PAZ; 1.
DR   PROSITE; PS50822; PIWI; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Reference proteome; RNA-mediated gene silencing.
FT   CHAIN         1    904       Protein argonaute 4A.
FT                                /FTId=PRO_0000378431.
FT   DOMAIN      268    388       PAZ. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00142}.
FT   DOMAIN      557    865       Piwi. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00150}.
FT   COMPBIAS     12     19       Poly-Pro.
FT   CONFLICT    300    300       L -> P (in Ref. 5; AK064813).
FT                                {ECO:0000305}.
SQ   SEQUENCE   904 AA;  100639 MW;  BAEB650CCA79E2E4 CRC64;
     MESNSGEIEE LPPPPPLPPN AEPIKTDDTK KLSKPKRALM ARSGCGKKGQ PIQLLTNHFK
     VSLKAADEFF HHYYVNLKYE DDRPVDGKGI GRKVLDKLQQ TYASELANKD FAYDGEKSLF
     TIGALPQVNN EFTVVLEDFN TGKSSANGGS PGNDSPGNDR KRVRRPYQTK TFKVELNFAA
     KIPMSAIAQA LRGQESENTQ EAIRVIDIIL RQHSAKQGCL LVRQSFFHNN PSNFVDLGGG
     VMGCRGFHSS FRATQSGLSL NIDVSTTMIV KPGPVVDFLL ANQKVDHPNK IDWAKAKRAL
     KNLRIKTSPA NTEYKIVGLS ERNCYEQMFT LKQRNGDGEP EGVEVSVYEY FVKNRGIELR
     YSGDFPCINV GKPKRPTYFP IELCSLVPLQ RYTKALSTLQ RSSLVEKSRQ KPEERMSVLS
     DVLKRSNYDS EPMLNSCGIS IARGFTQVAG RVLQAPKLKA GNGEDLFARN GRWNFNNKRL
     IKASSIEKWA VVNFSARCNI RDLVRDIIKC GGMKGIKVED PFDVIEEDPS MRRAPAARRV
     DGMIDKMQKK LPGQPKFLLC VLAERKNSDI YGPWKRKCLA EFGIITQCVA PTRVNDQYIT
     NVLLKINAKL GGLNSLLQIE TSPSIPLVSK VPTIILGMDV SHGSPGQSDI PSIAAVVSSR
     EWPLVSKYRA SVRSQSPKLE MIDGLFKPQG AQEDDGLIRE LLVDFYTSTG KRKPDQVIIF
     RDGVSESQFT QVLNIELDQI IEACKFLDEN WSPKFTLIVA QKNHHTKFFV PGSQNNVPPG
     TVVDNAVCHP RNNDFYMCAH AGMIGTTRPT HYHILHDEIG FSADDLQELV HSLSYVYQRS
     TTAISVVAPI CYAHLAAAQV SQFIKFDEMS ETSSSHGGHT SAGSAPVPEL PRLHNKVRSS
     MFFC
//
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