ID PAN_ARATH Reviewed; 452 AA.
AC Q9SX27; Q9ZPJ6;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 24-JAN-2024, entry version 145.
DE RecName: Full=Transcription factor PERIANTHIA;
DE AltName: Full=bZIP transcription factor 46;
DE Short=AtbZIP46;
GN Name=PAN; OrderedLocusNames=At1g68640; ORFNames=F24J5.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], DEVELOPMENTAL STAGE, FUNCTION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=9990857; DOI=10.1101/gad.13.3.334;
RA Chuang C.F., Running M.P., Williams R.W., Meyerowitz E.M.;
RT "The PERIANTHIA gene encodes a bZIP protein involved in the determination
RT of floral organ number in Arabidopsis thaliana.";
RL Genes Dev. 13:334-344(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP DISRUPTION PHENOTYPE.
RX PubMed=8620853; DOI=10.1242/dev.122.4.1261;
RA Running M.P., Meyerowitz E.M.;
RT "Mutations in the PERIANTHIA gene of Arabidopsis specifically alter floral
RT organ number and initiation pattern.";
RL Development 122:1261-1269(1996).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11906833; DOI=10.1016/s1360-1385(01)02223-3;
RA Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J.,
RA Tiedemann J., Kroj T., Parcy F.;
RT "bZIP transcription factors in Arabidopsis.";
RL Trends Plant Sci. 7:106-111(2002).
RN [8]
RP INTERACTION WITH BOP1 AND BOP2.
RX PubMed=15805484; DOI=10.1105/tpc.104.030536;
RA Hepworth S.R., Zhang Y., McKim S., Li X., Haughn G.W.;
RT "BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning
RT in Arabidopsis.";
RL Plant Cell 17:1434-1448(2005).
RN [9]
RP FUNCTION.
RX PubMed=19395638; DOI=10.1242/dev.035436;
RA Das P., Ito T., Wellmer F., Vernoux T., Dedieu A., Traas J.,
RA Meyerowitz E.M.;
RT "Floral stem cell termination involves the direct regulation of AGAMOUS by
RT PERIANTHIA.";
RL Development 136:1605-1611(2009).
RN [10]
RP FUNCTION.
RX PubMed=19395639; DOI=10.1242/dev.033647;
RA Maier A.T., Stehling-Sun S., Wollmann H., Demar M., Hong R.L., Haubeiss S.,
RA Weigel D., Lohmann J.U.;
RT "Dual roles of the bZIP transcription factor PERIANTHIA in the control of
RT floral architecture and homeotic gene expression.";
RL Development 136:1613-1620(2009).
RN [11]
RP INTERACTION WITH GRXC7/ROXY1, AND MUTAGENESIS OF CYS-340.
RX PubMed=19218396; DOI=10.1105/tpc.108.064477;
RA Li S., Lauri A., Ziemann M., Busch A., Bhave M., Zachgo S.;
RT "Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is
RT required for petal development in Arabidopsis thaliana.";
RL Plant Cell 21:429-441(2009).
CC -!- FUNCTION: Transcriptional activator involved in the determination of
CC floral organ number. Acts to determine floral organ patterning by
CC establishing floral organ primordia in specific numbers and positions.
CC Plays a role in regulating stem cell fate by directly controlling AG
CC expression. Binds to the 5'-AAGAAT-3' cis-acting element found in AG
CC promoter. Might represent a target for a post-translational
CC modification by GRXC7/ROXY1. {ECO:0000269|PubMed:19395638,
CC ECO:0000269|PubMed:19395639, ECO:0000269|PubMed:9990857}.
CC -!- SUBUNIT: Interacts with GRXC7/ROXY1. Interacts with BOP1 and BOP2.
CC {ECO:0000269|PubMed:15805484, ECO:0000269|PubMed:19218396}.
CC -!- INTERACTION:
CC Q9SX27; Q96305: GRXC7; NbExp=3; IntAct=EBI-2257975, EBI-2257898;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the apical meristem, the floral
CC meristem, each whorl of organ primordia, and in ovule primordia during
CC wild-type flower development. {ECO:0000269|PubMed:9990857}.
CC -!- DISRUPTION PHENOTYPE: Mutant plants have extra floral organs. The modal
CC numbers of organs in mutant flowers are 5 sepals, 5 petals, 5 stamens,
CC and 2 carpels in contrast with the tetramerous pattern of the wild
CC type. {ECO:0000269|PubMed:8620853, ECO:0000269|PubMed:9990857}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD19660.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF111711; AAD19660.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC008075; AAD49979.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34822.1; -; Genomic_DNA.
DR EMBL; AK118286; BAC42904.1; -; mRNA.
DR EMBL; BT008586; AAP40413.1; -; mRNA.
DR PIR; H96710; H96710.
DR RefSeq; NP_177031.1; NM_105536.4.
DR AlphaFoldDB; Q9SX27; -.
DR SMR; Q9SX27; -.
DR BioGRID; 28415; 3.
DR IntAct; Q9SX27; 5.
DR STRING; 3702.Q9SX27; -.
DR PaxDb; 3702-AT1G68640-1; -.
DR ProteomicsDB; 248659; -.
DR EnsemblPlants; AT1G68640.1; AT1G68640.1; AT1G68640.
DR GeneID; 843194; -.
DR Gramene; AT1G68640.1; AT1G68640.1; AT1G68640.
DR KEGG; ath:AT1G68640; -.
DR Araport; AT1G68640; -.
DR TAIR; AT1G68640; PAN.
DR eggNOG; ENOG502QWDU; Eukaryota.
DR HOGENOM; CLU_024782_1_3_1; -.
DR InParanoid; Q9SX27; -.
DR OMA; DSADKHH; -.
DR OrthoDB; 465017at2759; -.
DR PhylomeDB; Q9SX27; -.
DR PRO; PR:Q9SX27; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SX27; baseline and differential.
DR Genevisible; Q9SX27; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IPI:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0009909; P:regulation of flower development; IMP:TAIR.
DR CDD; cd14708; bZIP_HBP1b-like; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR025422; TGA_domain.
DR PANTHER; PTHR45693:SF1; TRANSCRIPTION FACTOR PERIANTHIA; 1.
DR PANTHER; PTHR45693; TRANSCRIPTION FACTOR TGA9; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF14144; DOG1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS51806; DOG1; 1.
PE 1: Evidence at protein level;
KW Activator; Coiled coil; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..452
FT /note="Transcription factor PERIANTHIA"
FT /id="PRO_0000398152"
FT DOMAIN 164..227
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT DOMAIN 233..449
FT /note="DOG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01147"
FT REGION 166..186
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 192..206
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT MUTAGEN 340
FT /note="C->A: Abolishes function in flower development."
FT /evidence="ECO:0000269|PubMed:19218396"
SQ SEQUENCE 452 AA; 50458 MW; 06CE2D1837AC261C CRC64;
MQSSFKTVPF TPDFYSQSSY FFRGDSCLEE FHQPVNGFHH EEAIDLSPNV TIASANLHYT
TFDTVMDCGG GGGGGLRERL EGGEEECLDT GQLVYQKGTR LVGGGVGEVN SSWCDSVSAM
ADNSQHTDTS TDIDTDDKTQ LNGGHQGMLL ATNCSDQSNV KSSDQRTLRR LAQNREAARK
SRLRKKAYVQ QLENSRIRLA QLEEELKRAR QQGSLVERGV SADHTHLAAG NGVFSFELEY
TRWKEEHQRM INDLRSGVNS QLGDNDLRVL VDAVMSHYDE IFRLKGIGTK VDVFHMLSGM
WKTPAERFFM WLGGFRSSEL LKILGNHVDP LTDQQLIGIC NLQQSSQQAE DALSQGMEAL
QQSLLETLSS ASMGPNSSAN VADYMGHMAM AMGKLGTLEN FLRQADLLRQ QTLQQLHRIL
TTRQAARAFL VIHDYISRLR ALSSLWLARP RD
//
