GenomeNet

Database: UniProt
Entry: Q9VDI1_DROME
LinkDB: Q9VDI1_DROME
Original site: Q9VDI1_DROME 
ID   Q9VDI1_DROME            Unreviewed;       494 AA.
AC   Q9VDI1; Q8SZZ4;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 2.
DT   18-JUL-2018, entry version 161.
DE   SubName: Full=LD46328p {ECO:0000313|EMBL:AAL39835.1};
DE   SubName: Full=Syndapin, isoform B {ECO:0000313|EMBL:AAF55812.2};
GN   Name=Synd {ECO:0000313|EMBL:AAF55812.2,
GN   ECO:0000313|FlyBase:FBgn0053094};
GN   Synonyms=CG15694 {ECO:0000313|EMBL:AAF55812.2}, D-Synd
GN   {ECO:0000313|EMBL:AAF55812.2}, Dmel\CG33094
GN   {ECO:0000313|EMBL:AAF55812.2}, synd {ECO:0000313|EMBL:AAF55812.2},
GN   syndapin {ECO:0000313|EMBL:AAL39835.1};
GN   ORFNames=CG33094 {ECO:0000313|EMBL:AAF55812.2,
GN   ECO:0000313|FlyBase:FBgn0053094}, Dmel_CG33094
GN   {ECO:0000313|EMBL:AAF55812.2};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803};
RN   [1] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
RA   Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
RA   Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
RA   Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2] {ECO:0000313|EMBL:AAL39835.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley {ECO:0000313|EMBL:AAL39835.1};
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,
RA   Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R.,
RA   Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J.,
RA   Nunoo J., Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K.,
RA   Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL   Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537568;
RA   Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA   Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA   George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA   Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA   Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA   Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT   "Finishing a whole-genome shotgun: release 3 of the Drosophila
RT   melanogaster euchromatic genome sequence.";
RL   Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN   [4] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [5] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537573;
RA   Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA   Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
RA   Ashburner M., Celniker S.E.;
RT   "The transposable elements of the Drosophila melanogaster euchromatin:
RT   a genomics perspective.";
RL   Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002).
RN   [6] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537574;
RA   Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA   Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA   Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA   Karpen G.H.;
RT   "Heterochromatic sequences in a Drosophila whole-genome shotgun
RT   assembly.";
RL   Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN   [7] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA   Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA   Ashburner M., Anxolabehere D.;
RT   "Combined evidence annotation of transposable elements in genome
RT   sequences.";
RL   PLoS Comput. Biol. 1:166-175(2005).
RN   [8] {ECO:0000313|EMBL:AAF55812.2}
RP   NUCLEOTIDE SEQUENCE.
RG   Berkeley Drosophila Genome Project;
RA   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA   Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
RA   Yu C., Rubin G.;
RT   "Drosophila melanogaster release 4 sequence.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:AAF55812.2}
RP   NUCLEOTIDE SEQUENCE.
RA   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA   Svirskas R., Rubin G.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569856; DOI=10.1126/science.1139815;
RA   Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT   "The Release 5.1 annotation of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1586-1591(2007).
RN   [11] {ECO:0000313|EMBL:AAF55812.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569867; DOI=10.1126/science.1139816;
RA   Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA   Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA   Dimitri P., Karpen G.H., Celniker S.E.;
RT   "Sequence finishing and mapping of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1625-1628(2007).
RN   [12] {ECO:0000213|PDB:3I2W}
RP   X-RAY CRYSTALLOGRAPHY (2.67 ANGSTROMS) OF 14-303.
RX   PubMed=19997509; DOI=10.1371/journal.pone.0008150;
RA   Edeling M.A., Sanker S., Shima T., Umasankar P.K., Honing S.,
RA   Kim H.Y., Davidson L.A., Watkins S.C., Tsang M., Owen D.J.,
RA   Traub L.M.;
RT   "Structural requirements for PACSIN/Syndapin operation during
RT   zebrafish embryonic notochord development.";
RL   PLoS ONE 4:e8150-e8150(2009).
RN   [13] {ECO:0000313|EMBL:AAF55812.2}
RP   NUCLEOTIDE SEQUENCE.
RG   FlyBase;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AE014297; AAF55812.2; -; Genomic_DNA.
DR   EMBL; AY069690; AAL39835.1; -; mRNA.
DR   RefSeq; NP_788697.1; NM_176520.2.
DR   UniGene; Dm.2000; -.
DR   PDB; 3I2W; X-ray; 2.67 A; A/B=14-303.
DR   PDBsum; 3I2W; -.
DR   SMR; Q9VDI1; -.
DR   IntAct; Q9VDI1; 5.
DR   STRING; 7227.FBpp0083373; -.
DR   PRIDE; Q9VDI1; -.
DR   EnsemblMetazoa; FBtr0083966; FBpp0083373; FBgn0053094.
DR   GeneID; 42467; -.
DR   UCSC; CG33094-RB; d. melanogaster.
DR   CTD; 42467; -.
DR   FlyBase; FBgn0053094; Synd.
DR   eggNOG; KOG2856; Eukaryota.
DR   eggNOG; ENOG410XRX2; LUCA.
DR   GeneTree; ENSGT00510000046376; -.
DR   OrthoDB; EOG091G0AS9; -.
DR   Reactome; R-DME-8856828; Clathrin-mediated endocytosis.
DR   ChiTaRS; Synd; fly.
DR   GenomeRNAi; 42467; -.
DR   Proteomes; UP000000803; Chromosome 3R.
DR   Bgee; FBgn0053094; -.
DR   GO; GO:0032154; C:cleavage furrow; IDA:FlyBase.
DR   GO; GO:0030496; C:midbody; IDA:FlyBase.
DR   GO; GO:0005886; C:plasma membrane; IDA:FlyBase.
DR   GO; GO:0045211; C:postsynaptic membrane; IDA:FlyBase.
DR   GO; GO:0071212; C:subsynaptic reticulum; IDA:FlyBase.
DR   GO; GO:0008289; F:lipid binding; IDA:FlyBase.
DR   GO; GO:0005543; F:phospholipid binding; ISM:FlyBase.
DR   GO; GO:0036090; P:cleavage furrow ingression; IMP:FlyBase.
DR   GO; GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.
DR   GO; GO:0061024; P:membrane organization; IDA:FlyBase.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:FlyBase.
DR   GO; GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.
DR   GO; GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.
DR   GO; GO:0007053; P:spindle assembly involved in male meiosis; IMP:FlyBase.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; NAS:FlyBase.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0000213|PDB:3I2W};
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077,
KW   ECO:0000256|SAAS:SAAS00803874, ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000803};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q9VDI1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW   SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192,
KW   ECO:0000256|SAAS:SAAS00989295}.
FT   DOMAIN       10    280       F-BAR. {ECO:0000259|PROSITE:PS51741}.
FT   DOMAIN      436    494       SH3. {ECO:0000259|PROSITE:PS50002}.
FT   COILED      185    212       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   494 AA;  55910 MW;  447B789F56E61B10 CRC64;
     MSHHSDDQLL QAGSDSFWEP GNYKRTTKRI EDGYKLCNDL QQLIQERADI EKGYAKSLRT
     WSKKWGELIE KGPEYGTTEA AWKGVLTESE RISDVHMKIK DNLCNDVNSQ IKTWQKENYH
     HTLMQIKERK DLEDLFKKAQ KPWAKLLAKV EKAKADYHSA CKTERSATNQ ERNANADSSL
     SPDQVKKMHD RVQKTKDQVQ KCREKYEQAI AEITKYNSVY IEDMTSVFEK CQTFEKTRLQ
     FFKEILFNVH SCLDLTKVQS LPQIYEEFSH TINNADQQKD LKWWSNNHGI NMAMNWPSFV
     EYTEEFRDIA KGNKSKEALP AAPITLINQR PVAEDVHEYP QTNSLKKNTS TLSSVSSRAS
     VKSEIATTQS SVTTSEAKTS AAVAGAATAT AAATAASAAS NRNSSVTNGN GKVDANPFDE
     EEEWDESDNV LVDNGEPGVP VKALYDYEGA ESDELTFKQG DVFEKLEDED EQGWCKGRMN
     GRVGLYPANY VETA
//
DBGET integrated database retrieval system