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Database: UniProt
Entry: Q9VPU9_DROME
LinkDB: Q9VPU9_DROME
Original site: Q9VPU9_DROME 
ID   Q9VPU9_DROME            Unreviewed;       628 AA.
AC   Q9VPU9; Q95R52;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 2.
DT   10-OCT-2018, entry version 134.
DE   SubName: Full=PNUTS, isoform A {ECO:0000313|EMBL:AAF51439.2};
DE   SubName: Full=PNUTS, isoform B {ECO:0000313|EMBL:AAF51438.2};
DE   SubName: Full=SD07532p {ECO:0000313|EMBL:AAL29158.1};
GN   Name=PNUTS {ECO:0000313|EMBL:AAF51439.2,
GN   ECO:0000313|FlyBase:FBgn0053526};
GN   Synonyms=CG31657 {ECO:0000313|EMBL:AAF51439.2}, Dmel\CG33526
GN   {ECO:0000313|EMBL:AAF51439.2}, Pnuts {ECO:0000313|EMBL:AAF51439.2},
GN   PNUTS-RB {ECO:0000313|EMBL:AAF51439.2}, PNUTSDm
GN   {ECO:0000313|EMBL:AAF51439.2};
GN   ORFNames=CG33526 {ECO:0000313|EMBL:AAF51438.2,
GN   ECO:0000313|FlyBase:FBgn0053526}, CG4124
GN   {ECO:0000313|EMBL:AAF51439.2}, Dmel_CG33526
GN   {ECO:0000313|EMBL:AAF51439.2};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803};
RN   [1] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
RA   Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
RA   Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
RA   Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2] {ECO:0000313|EMBL:AAL29158.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,
RA   Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R.,
RA   Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J.,
RA   Nunoo J., Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K.,
RA   Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL   Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537568;
RA   Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA   Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA   George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA   Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA   Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA   Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT   "Finishing a whole-genome shotgun: release 3 of the Drosophila
RT   melanogaster euchromatic genome sequence.";
RL   Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN   [4] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [5] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537573;
RA   Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA   Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
RA   Ashburner M., Celniker S.E.;
RT   "The transposable elements of the Drosophila melanogaster euchromatin:
RT   a genomics perspective.";
RL   Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002).
RN   [6] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537574;
RA   Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA   Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA   Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA   Karpen G.H.;
RT   "Heterochromatic sequences in a Drosophila whole-genome shotgun
RT   assembly.";
RL   Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN   [7] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA   Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA   Ashburner M., Anxolabehere D.;
RT   "Combined evidence annotation of transposable elements in genome
RT   sequences.";
RL   PLoS Comput. Biol. 1:166-175(2005).
RN   [8] {ECO:0000313|EMBL:AAF51439.2}
RP   NUCLEOTIDE SEQUENCE.
RA   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA   Svirskas R., Rubin G.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:AAF51439.2}
RP   NUCLEOTIDE SEQUENCE.
RG   Berkeley Drosophila Genome Project;
RA   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA   Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
RA   Yu C., Rubin G.;
RT   "Drosophila melanogaster release 4 sequence.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569856; DOI=10.1126/science.1139815;
RA   Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT   "The Release 5.1 annotation of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1586-1591(2007).
RN   [11] {ECO:0000313|EMBL:AAF51439.2, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569867; DOI=10.1126/science.1139816;
RA   Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA   Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA   Dimitri P., Karpen G.H., Celniker S.E.;
RT   "Sequence finishing and mapping of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1625-1628(2007).
RN   [12] {ECO:0000313|EMBL:AAF51439.2}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=26109357;
RG   FlyBase Consortium;
RA   Matthews B.B., Dos Santos G., Crosby M.A., Emmert D.B.,
RA   St Pierre S.E., Gramates L.S., Zhou P., Schroeder A.J., Falls K.,
RA   Strelets V., Russo S.M., Gelbart W.M.;
RT   "Gene Model Annotations for Drosophila melanogaster: Impact of High-
RT   Throughput Data.";
RL   G3 (Bethesda) 5:1721-1736(2015).
RN   [13] {ECO:0000313|EMBL:AAF51439.2}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=26109356;
RG   FlyBase Consortium;
RA   Crosby M.A., Gramates L.S., Dos Santos G., Matthews B.B.,
RA   St Pierre S.E., Zhou P., Schroeder A.J., Falls K., Emmert D.B.,
RA   Russo S.M., Gelbart W.M.;
RT   "Gene Model Annotations for Drosophila melanogaster: The Rule-
RT   Benders.";
RL   G3 (Bethesda) 5:1737-1749(2015).
RN   [14] {ECO:0000313|EMBL:AAF51439.2}
RP   NUCLEOTIDE SEQUENCE.
RG   FlyBase;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
CC       ProRule:PRU00649}.
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DR   EMBL; AE014134; AAF51438.2; -; Genomic_DNA.
DR   EMBL; AE014134; AAF51439.2; -; Genomic_DNA.
DR   EMBL; AY061610; AAL29158.1; -; mRNA.
DR   RefSeq; NP_001014454.1; NM_001014454.2.
DR   RefSeq; NP_001014455.1; NM_001014455.2.
DR   UniGene; Dm.3526; -.
DR   EnsemblMetazoa; FBtr0091486; FBpp0077686; FBgn0053526.
DR   EnsemblMetazoa; FBtr0091487; FBpp0077684; FBgn0053526.
DR   GeneID; 33270; -.
DR   UCSC; CG33526-RA; d. melanogaster.
DR   CTD; 33270; -.
DR   FlyBase; FBgn0053526; PNUTS.
DR   eggNOG; ENOG410IGTC; Eukaryota.
DR   eggNOG; ENOG410XP4M; LUCA.
DR   GeneTree; ENSGT00530000063820; -.
DR   OrthoDB; EOG091G07K1; -.
DR   GenomeRNAi; 33270; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   Bgee; FBgn0053526; Expressed in 32 organ(s), highest expression level in antenna.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IPI:FlyBase.
DR   GO; GO:0048589; P:developmental growth; IMP:FlyBase.
DR   GO; GO:0010467; P:gene expression; IMP:FlyBase.
DR   InterPro; IPR019350; RNA_pol_I-sp_TIF_RRN6-like.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF10214; Rrn6; 1.
DR   SUPFAM; SSF47676; SSF47676; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000803};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q9VPU9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000803}.
FT   DOMAIN       71    145       TFIIS N-terminal. {ECO:0000259|PROSITE:
FT                                PS51319}.
SQ   SEQUENCE   628 AA;  66554 MW;  4492737427034F2C CRC64;
     MPRIVPLQLL RCLRVLLDNN GGILSAVEVK RISGLMAKYS KKLVSKCVYV QILKSTKTEL
     LGDFMAVGGW SLVYTWLNDA IRAMNWPLVQ EILELLLLSP VDVNRLKINS APILVKGLCK
     DGGNEGVRIL AKRLVEQWLK IVTENTSMTI QGAAPHIAAT TASQVPASVS GAGSASVPDS
     ASSSDSTDSA GAPVTYTITS AANSSNSNSI TIKWKPLLDN PDGGDETDSG TQSKDNEVEH
     LEKGSSATHL LADASLGKKS GLDDSSSAAE VKSGEDVDNK KHKSSKSDKS KRSEKEREKD
     RKKESSSHRS SSSSHKSSSS SSSSSSKSSS SKSSSSSSSS HRSSSDKYRD KDKARSSSGS
     SSSSKDRERS SGSSSSSSNK HKSSKSSSSS SSSSSSSSGS SSSKDRKSSS STSSSSSSSR
     QDKDKDNKLM PPPAVAASNA AGTSPTASAK ESDAQKPRSI PIMSRKASIS IEIRRDTEKT
     ATVKTYQSKF RSHGLTEEAP PPPSRKGLKK PTSSAVAASP ALMAVPSSLK RPSPPPRDLS
     TDKKAKIDIN NVAGHVERPG AAKLIAPKKS KQQMLESLLM LFSILFHSPR TLVAFAFVFD
     RSRMSNSAVL FVDLHSILKV FNFAWGGS
//
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