ID Q9VXM0_DROME Unreviewed; 2009 AA.
AC Q9VXM0;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 178.
DE SubName: Full=LDL receptor related protein 4, isoform B {ECO:0000313|EMBL:AAF48538.1};
GN Name=Lrp4 {ECO:0000313|EMBL:AAF48538.1,
GN ECO:0000313|FlyBase:FBgn0030706};
GN Synonyms=CT25574 {ECO:0000313|EMBL:AAF48538.1}, Dm CG8909
GN {ECO:0000313|EMBL:AAF48538.1}, Dmel\CG8909
GN {ECO:0000313|EMBL:AAF48538.1}, LRP4 {ECO:0000313|EMBL:AAF48538.1},
GN lrp4 {ECO:0000313|EMBL:AAF48538.1};
GN ORFNames=CG8909 {ECO:0000313|EMBL:AAF48538.1,
GN ECO:0000313|FlyBase:FBgn0030706}, Dmel_CG8909
GN {ECO:0000313|EMBL:AAF48538.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803};
RN [1] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A.,
RA An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E.,
RA Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C.,
RA Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A.,
RA Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C.,
RA Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G.,
RA Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.,
RA Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537568;
RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster
RT euchromatic genome sequence.";
RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN [3] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537573;
RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M.,
RA Celniker S.E.;
RT "The transposable elements of the Drosophila melanogaster euchromatin: a
RT genomics perspective.";
RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN [5] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537574;
RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA Karpen G.H.;
RT "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.";
RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN [6] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA Ashburner M., Anxolabehere D.;
RT "Combined evidence annotation of transposable elements in genome
RT sequences.";
RL PLoS Comput. Biol. 1:166-175(2005).
RN [7] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569856; DOI=10.1126/science.1139815;
RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.";
RL Science 316:1586-1591(2007).
RN [8] {ECO:0000313|EMBL:AAF48538.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569867; DOI=10.1126/science.1139816;
RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA Dimitri P., Karpen G.H., Celniker S.E.;
RT "Sequence finishing and mapping of Drosophila melanogaster
RT heterochromatin.";
RL Science 316:1625-1628(2007).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; AE014298; AAF48538.1; -; Genomic_DNA.
DR RefSeq; NP_727914.1; NM_167474.3.
DR AlphaFoldDB; Q9VXM0; -.
DR SMR; Q9VXM0; -.
DR IntAct; Q9VXM0; 1.
DR STRING; 7227.FBpp0073931; -.
DR PaxDb; 7227-FBpp0073931; -.
DR DNASU; 32552; -.
DR EnsemblMetazoa; FBtr0074125; FBpp0073931; FBgn0030706.
DR GeneID; 32552; -.
DR UCSC; CG8909-RB; d. melanogaster.
DR AGR; FB:FBgn0030706; -.
DR CTD; 4038; -.
DR FlyBase; FBgn0030706; Lrp4.
DR VEuPathDB; VectorBase:FBgn0030706; -.
DR eggNOG; KOG1215; Eukaryota.
DR GeneTree; ENSGT00940000158366; -.
DR HOGENOM; CLU_000085_4_0_1; -.
DR InParanoid; Q9VXM0; -.
DR OMA; NNRYTAI; -.
DR OrthoDB; 3107655at2759; -.
DR PhylomeDB; Q9VXM0; -.
DR BioGRID-ORCS; 32552; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 32552; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0030706; Expressed in brain and 10 other cell types or tissues.
DR ExpressionAtlas; Q9VXM0; baseline and differential.
DR Genevisible; Q9VXM0; DM.
DR GO; GO:0043679; C:axon terminus; IDA:FlyBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0097060; C:synaptic membrane; ISS:FlyBase.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:1990709; P:presynaptic active zone organization; IMP:FlyBase.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00112; LDLa; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 7.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 4.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR46513:SF13; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 3.
DR Pfam; PF00057; Ldl_recept_a; 6.
DR Pfam; PF00058; Ldl_recept_b; 12.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00192; LDLa; 7.
DR SMART; SM00135; LY; 20.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 6.
DR SUPFAM; SSF63825; YWTD domain; 4.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01209; LDLRA_1; 4.
DR PROSITE; PS50068; LDLRA_2; 7.
DR PROSITE; PS51120; LDLRB; 15.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAF48538.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..2009
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004335329"
FT TRANSMEM 1889..1914
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 589..604
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT REPEAT 651..693
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 694..736
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 737..780
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 781..823
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 965..1007
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1008..1050
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1051..1094
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1095..1136
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1269..1311
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1312..1354
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1355..1398
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1399..1440
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1576..1619
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1620..1662
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1663..1706
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REGION 89..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1855..1881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 246..261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 267..279
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 274..292
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 286..301
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 306..318
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 313..331
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 325..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 375..390
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 397..409
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 404..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 416..431
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 442..454
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 449..467
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 461..476
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 506..521
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 2009 AA; 225895 MW; E672797A34D2F4E1 CRC64;
MYLTAFPFWP LVCFVWLCLG LGDLTKTAVK RNAPHYGIHP TNALGRWDWN KHKQLHSDAR
IGHLEAGNES REDQLSEELS KFGEKLFPVS NYPPYQQNNE DSQEVHHSGE GRLHTMESSV
PSKTRISGGT NSNDTPKFRN IGAQRGRTEI AGIRETDRIS SRGRDGFIGG PSNKQKPFRV
NLAVLVQDDP SQPGETYSNC QNSNESDENC NPEEDAVPNL QRDCEKTGIH VMCPRTFRCI
SKYWLCDGDD DCGDYSDETH CGARTNCTDD QFECLNGFCI PRTWVCDGEN DCKDFSDETH
CNRTTCTDEH FTCNDGYCIS LAFRCDGEHD CNDNSDELKC AAVINSCPEG EFKCRGGLGG
AGGPSGQCIL NRFRCDGDND CGDWSDEENC PQKPSLCTSN EYKCADGTCI PKRWKCDKEQ
DCDGGEDEND CGSLGSEHPL TCGSDEFTCN NGRCILKTWL CDGYPDCAAG EDEVECHLQC
DLGQFLCPTK QNLTNLKICV HQKHICDGHN ECPAGEDEAD CPKERKCSEP SPCEQLCIET
TAGSNECACR LGYVMDKNKV NCTDIDECQY LTSPVCSQKC HNTMGSFKCS CETGYILRPD
LRSCKALGGA MTLLVANRWD IRRVTLSNNR YSAIVKGLHN AIALDFHHRK GLMFWSDVST
DVIKMVYMNG TRVRDVIKWG LESPGGIAVD WIHDLLFWTD SGTRRVEVSN FQGNLRTVIA
SYDLDKPRAI VVHPGEALAF WSDWGPNPKI ERAYMDGTQR KVIISKGVTW PNGLAIDFPN
SKIYWADAKQ HAIECSNLDG SDRNKILSTH LPHPFALTLF EDTMYWTDWN TKTVSAADKI
TGKEFRAVHE NFHFPMDIHA YHPARQPEYA DRCQKDRRGL RGGCSHLCLP NKTSRRCGCP
IGLSLKEDGK TCKSTADKLV LVARRKDIRL RHLRDNQADP NDVDMIVPLD NLKHAVALDW
CSDTDFIYWT DVERSTINKA HLNGSYQQRV VHSNLVSPVG LALDWITDKL YWTDPSTNRI
EVATTNGKMR TLLIWEKLYK PRDIVVNPIE GFMFWSDWGD DPMIERANMD GHERVTITSK
KLIYPNGLAI DYEKSKIYFV DGGTKTLENM NFDGSGRQVI LNGLGHPFGL DVNEGRVFWT
DWDTKSVMSA NKLTGKDTNV IIANSTDLMD IRVFHRTRRR IFNACDKLNG GCSHLCLLNP
TSYTCACTVG VQLKEDRHTC SEGPTQYILF AHRIDIRQIS LDFDHLIDVV LPLPPISNAV
ALDVDRKTGY IYWSDTIENV IMSSSPDGLH VQKIVGDSLE NPDGLVVDSI GRTIYWADAG
RHTIEVASLD GSNRHVIAYK DLESPRGLAL DYEAGLLFWT DWGHYRKIER SHLDGNERSR
IVTANLGWPN GLSLDLKSKR IYWVDARLKT IDSCDYTGNQ RKLIMSSLHH PYALALSDDN
IYWTDWKSKA LHMTERRNIS AKRDIITNID GLMDIKIIYQ NQNQSTMKNA CGNNNGNCSH
LCLRNPSGYS CQCPIGLRLR QNSTTQCQNL PEDYLLIALR SGIGMISLNS GDFMDVVLPI
NGVHGAVVLD YHYRKNLLFF ADVNLDVIRR VNLLNLTESK VIVGTDVLTP NGIAVDWIAD
NLYWSDTDRK LIEVSRLDGS CRKRIVEDNL GDPRSLIVHP KKAYLFWSDW SSPAKIERSY
LDGSNRTVII TSGIGFPTGL TIDFTNRRLL WADALEDNIG QVDFNGKRRQ TIVPYAPHPF
GLTLFENSIF WTDWYNKSVY RSQKLARSGY GNPFEVRDAL SGALDIRAVS LSRQPKSVNH
CAQDNGGCTH LCLNRNVDYV CACPDVMDPK DVACSIKPKV LVHANLENDQ LLEYSDESTD
DSTPPELLGE SNDHGDDGHT KKSDQEREFF VLVALGVVIV MVVIIILVIF MLAFNTSKKK
NKRNSRGSSR SVLTFSNPNY NVDGTPMEPK TNIWKRFKYD KTHQERAGVY EERSLTTETA
SSSLFVPTPS PMASPSTKTI QLTTLSTIT
//
