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Database: UniProt
Entry: Q9VYG8_DROME
LinkDB: Q9VYG8_DROME
Original site: Q9VYG8_DROME 
ID   Q9VYG8_DROME            Unreviewed;       252 AA.
AC   Q9VYG8;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   18-JUL-2018, entry version 136.
DE   SubName: Full=CG15717-PA {ECO:0000313|EMBL:CAQ53399.1};
DE   SubName: Full=RE15818p {ECO:0000313|EMBL:AAL48715.1};
DE   SubName: Full=RE20610p {ECO:0000313|EMBL:AAM29429.1};
GN   Name=Dmel\CG15717 {ECO:0000313|EMBL:AAF48229.1};
GN   ORFNames=CG15717 {ECO:0000313|EMBL:AAF48229.1,
GN   ECO:0000313|FlyBase:FBgn0030451}, Dmel_CG15717
GN   {ECO:0000313|EMBL:AAF48229.1};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803};
RN   [1] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
RA   Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
RA   Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
RA   Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2] {ECO:0000313|EMBL:AAL48715.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley {ECO:0000313|EMBL:AAL48715.1};
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,
RA   Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,
RA   George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G.,
RA   Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S.,
RA   Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M.,
RA   Celniker S.;
RL   Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537568;
RA   Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA   Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA   George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA   Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA   Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA   Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT   "Finishing a whole-genome shotgun: release 3 of the Drosophila
RT   melanogaster euchromatic genome sequence.";
RL   Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN   [4] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [5] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537573;
RA   Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA   Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
RA   Ashburner M., Celniker S.E.;
RT   "The transposable elements of the Drosophila melanogaster euchromatin:
RT   a genomics perspective.";
RL   Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002).
RN   [6] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537574;
RA   Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA   Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA   Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA   Karpen G.H.;
RT   "Heterochromatic sequences in a Drosophila whole-genome shotgun
RT   assembly.";
RL   Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN   [7] {ECO:0000313|EMBL:AAM29429.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley {ECO:0000313|EMBL:AAM29429.1};
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,
RA   Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,
RA   George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G.,
RA   Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S.,
RA   Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M.,
RA   Celniker S.;
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA   Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA   Ashburner M., Anxolabehere D.;
RT   "Combined evidence annotation of transposable elements in genome
RT   sequences.";
RL   PLoS Comput. Biol. 1:166-175(2005).
RN   [9] {ECO:0000313|EMBL:AAF48229.1}
RP   NUCLEOTIDE SEQUENCE.
RG   Berkeley Drosophila Genome Project;
RA   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA   Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
RA   Yu C., Rubin G.;
RT   "Drosophila melanogaster release 4 sequence.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:AAF48229.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA   Svirskas R., Rubin G.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [11] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569856; DOI=10.1126/science.1139815;
RA   Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT   "The Release 5.1 annotation of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1586-1591(2007).
RN   [12] {ECO:0000313|EMBL:AAF48229.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569867; DOI=10.1126/science.1139816;
RA   Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA   Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA   Dimitri P., Karpen G.H., Celniker S.E.;
RT   "Sequence finishing and mapping of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1625-1628(2007).
RN   [13] {ECO:0000313|EMBL:CAQ53399.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ZBMEL84 {ECO:0000313|EMBL:CAQ53399.1};
RX   PubMed=18477586; DOI=10.1093/molbev/msn111;
RA   Baines J.F., Sawyer S.A., Hartl D.L., Parsch J.;
RT   "Effects of X-linkage and sex-biased gene expression on the rate of
RT   adaptive protein evolution in Drosophila.";
RL   Mol. Biol. Evol. 25:1639-1650(2008).
RN   [14] {ECO:0000313|EMBL:CAR94078.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MEL02 {ECO:0000313|EMBL:CAR94078.1}, MEL11
RC   {ECO:0000313|EMBL:CAR94079.1}, MEL13 {ECO:0000313|EMBL:CAR94081.1},
RC   MEL15 {ECO:0000313|EMBL:CAR94082.1}, MEL16
RC   {ECO:0000313|EMBL:CAR94083.1}, MEL17 {ECO:0000313|EMBL:CAR94084.1},
RC   MEL18 {ECO:0000313|EMBL:CAR94085.1}, and MEL20
RC   {ECO:0000313|EMBL:CAR94087.1};
RX   PubMed=19126864; DOI=10.1093/molbev/msn297;
RA   Parsch J., Zhang Z., Baines J.F.;
RT   "The influence of demography and weak selection on the McDonald-
RT   Kreitman test: an empirical study in Drosophila.";
RL   Mol. Biol. Evol. 26:691-698(2009).
RN   [15] {ECO:0000313|EMBL:AAF48229.1}
RP   NUCLEOTIDE SEQUENCE.
RG   FlyBase;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AE014298; AAF48229.1; -; Genomic_DNA.
DR   EMBL; AY071093; AAL48715.1; -; mRNA.
DR   EMBL; AY113424; AAM29429.1; -; mRNA.
DR   EMBL; AE014298; AHN59656.1; -; Genomic_DNA.
DR   EMBL; AE014298; AHN59657.1; -; Genomic_DNA.
DR   EMBL; AM999037; CAQ53399.1; -; Genomic_DNA.
DR   EMBL; FM246152; CAR94078.1; -; Genomic_DNA.
DR   EMBL; FM246153; CAR94079.1; -; Genomic_DNA.
DR   EMBL; FM246155; CAR94081.1; -; Genomic_DNA.
DR   EMBL; FM246156; CAR94082.1; -; Genomic_DNA.
DR   EMBL; FM246157; CAR94083.1; -; Genomic_DNA.
DR   EMBL; FM246158; CAR94084.1; -; Genomic_DNA.
DR   EMBL; FM246159; CAR94085.1; -; Genomic_DNA.
DR   EMBL; FM246161; CAR94087.1; -; Genomic_DNA.
DR   RefSeq; NP_001285186.1; NM_001298257.1.
DR   RefSeq; NP_001285187.1; NM_001298258.1.
DR   RefSeq; NP_572856.1; NM_132628.3.
DR   UniGene; Dm.5328; -.
DR   IntAct; Q9VYG8; 6.
DR   STRING; 7227.FBpp0073554; -.
DR   PRIDE; Q9VYG8; -.
DR   EnsemblMetazoa; FBtr0073723; FBpp0073554; FBgn0030451.
DR   EnsemblMetazoa; FBtr0339676; FBpp0308733; FBgn0030451.
DR   EnsemblMetazoa; FBtr0344608; FBpp0310939; FBgn0030451.
DR   GeneID; 32262; -.
DR   KEGG; dme:Dmel_CG15717; -.
DR   UCSC; CG15717-RA; d. melanogaster.
DR   FlyBase; FBgn0030451; CG15717.
DR   eggNOG; ENOG410JJWI; Eukaryota.
DR   eggNOG; ENOG410ZDH9; LUCA.
DR   GeneTree; ENSGT00540000073372; -.
DR   OMA; KNYHYES; -.
DR   OrthoDB; EOG091G051N; -.
DR   GenomeRNAi; 32262; -.
DR   Proteomes; UP000000803; Chromosome X.
DR   Bgee; FBgn0030451; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR009961; DUF1487.
DR   PANTHER; PTHR21644; PTHR21644; 1.
DR   Pfam; PF07368; DUF1487; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000803};
KW   Oxidoreductase {ECO:0000313|EMBL:AAF48229.1};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:Q9VYG8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000803}.
SQ   SEQUENCE   252 AA;  27767 MW;  217DC456F86FE1A5 CRC64;
     MASNFTQSQP SRITSYMVNQ LQPTAQETKL ALIPSAPQWR SPQLMVVFED GDLHSARHQL
     LQSLQNPFAE GSVATLLLQE SIADQFVGLV AQDLRPLSQE VSKHPSYTST LAKIEELKAK
     TVQGESLKAG ESPVLVYDCV HSYLGNGATG VVTVHTFRTA KEAGQLAKRD PLPYGQVSLW
     NEKLGCAYEL IPRLPSDIVA INCFNPDLDP IWESFAADRN DVLLAKNYHY ESLVVSGKRR
     IVVFPVGTIF GN
//
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