ID Q9WYP8_THEMA Unreviewed; 273 AA.
AC Q9WYP8; G4FHX6;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=Ferrous iron transport permease EfeU {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=TM_0417 {ECO:0000313|EMBL:AAD35502.1};
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Thermotoga.
OX NCBI_TaxID=243274 {ECO:0000313|EMBL:AAD35502.1, ECO:0000313|Proteomes:UP000008183};
RN [1] {ECO:0000313|EMBL:AAD35502.1, ECO:0000313|Proteomes:UP000008183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8
RC {ECO:0000313|Proteomes:UP000008183};
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D., Heidelberg J.,
RA Sutton G.G., Fleischmann R.D., White O., Salzberg S.L., Smith H.O.,
RA Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
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DR EMBL; AE000512; AAD35502.1; -; Genomic_DNA.
DR PIR; A72378; A72378.
DR RefSeq; NP_228227.1; NC_000853.1.
DR RefSeq; WP_004083270.1; NZ_CP011107.1.
DR AlphaFoldDB; Q9WYP8; -.
DR PaxDb; 243274-THEMA_02640; -.
DR EnsemblBacteria; AAD35502; AAD35502; TM_0417.
DR KEGG; tma:TM0417; -.
DR KEGG; tmw:THMA_0423; -.
DR PATRIC; fig|243274.17.peg.415; -.
DR InParanoid; Q9WYP8; -.
DR OrthoDB; 8215804at2; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0034755; P:iron ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF2; PLASMA MEMBRANE IRON PERMEASE; 1.
DR Pfam; PF03239; FTR1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 273 AA; 30856 MW; DE4DB63DE7389E87 CRC64;
MHLGALLITF REALEASVII AVILAYLKRT GRETQKREVW LGMFFSIFAS LVLGAIVIWF
YGGIEEKELF ESVASYVAVV VLTSMIYWMA TKGKSIKSEI ERKVSKVISR WALIGFVFVV
VFREGFETVL FVTPFMTQNL AGTVVGIVLG LIFAGAIAYT LYVVGVKINL RRFFYYSSIL
LIFVAAGLVG YGTHEFIEWS EEKGFDLGFF EKEAYNLGIP ESSVWHHKGL IGSILMVLFG
YSVKMEWGRV LVQFGYLVLA LILITRAYKR KEI
//
