ID Q9WZX4_THEMA Unreviewed; 583 AA.
AC Q9WZX4; G4FCV4;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:AAD35952.1};
GN OrderedLocusNames=TM_0870 {ECO:0000313|EMBL:AAD35952.1};
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Thermotoga.
OX NCBI_TaxID=243274 {ECO:0000313|EMBL:AAD35952.1, ECO:0000313|Proteomes:UP000008183};
RN [1] {ECO:0000313|EMBL:AAD35952.1, ECO:0000313|Proteomes:UP000008183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8
RC {ECO:0000313|Proteomes:UP000008183};
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D., Heidelberg J.,
RA Sutton G.G., Fleischmann R.D., White O., Salzberg S.L., Smith H.O.,
RA Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
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DR EMBL; AE000512; AAD35952.1; -; Genomic_DNA.
DR PIR; A72323; A72323.
DR RefSeq; NP_228679.1; NC_000853.1.
DR RefSeq; WP_004080731.1; NZ_CP011107.1.
DR AlphaFoldDB; Q9WZX4; -.
DR PaxDb; 243274-THEMA_00285; -.
DR DNASU; 898543; -.
DR EnsemblBacteria; AAD35952; AAD35952; TM_0870.
DR KEGG; tma:TM0870; -.
DR KEGG; tmw:THMA_0892; -.
DR PATRIC; fig|243274.17.peg.871; -.
DR InParanoid; Q9WZX4; -.
DR OrthoDB; 9757901at2; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0008658; F:penicillin binding; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IBA:GO_Central.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000008183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 522..581
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 583 AA; 64834 MW; C633F9DD56DF951A CRC64;
MEKRLWLLLA IFAIFLTVSF MNLFFFPLAG ERENWFVSIP PRRGSVLDVR GRKIVYDSPE
YVAYLDVDFF KRQNGDIKAL EKTLQNCGIT KSAEEVMEYK FFKLTEGEDK VDVLKKIESE
LLPFVNIELV YTRKKIQDYA TGILLGTVID GTGKGGIEGF FDDQLQGKRK GFLELRYRGA
RLSPTLVNYS PPENGKDVWL SLDLDLQRRV YDIISKAVEG NSAEAGHVIV MESKTGRILS
MVTTRNWNDL IGGYIEPGST IKPLVYAIAL ETHSASPDFT VECEGSIKPV EQLPVIIRDI
EKHGLVDFSA GIVKSCNVMS VKVGELITEK TGVEGFYEWL RKVGFGEKTG IEMEGEIAGV
LREPKKWSLI DPAEISIGQG IGVTPVQLIA SLNIFANDGY WVKPTILKDS PVKKRRVFSK
ETTDVIRQAM VRVVEEGTGK LAQVKGIAIA GKTGTAQKAV GGEYRNLYHS LFVGFFPAED
PKYTILVHLD SPSGAFYGGE VAAPVFREIV EILTEKEDGR IRIVKGLMPD LRGLPVRDAL
LVLESLGVKD VEIKGKGWKV SEQTPPPNHP LEGPVILFLS DQK
//
