ID Q9X0V8_THEMA Unreviewed; 832 AA.
AC Q9X0V8; G4FEB5;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Alpha-mannosidase-related protein {ECO:0000313|EMBL:AAD36306.1};
GN OrderedLocusNames=TM_1231 {ECO:0000313|EMBL:AAD36306.1};
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Thermotoga.
OX NCBI_TaxID=243274 {ECO:0000313|EMBL:AAD36306.1, ECO:0000313|Proteomes:UP000008183};
RN [1] {ECO:0000313|EMBL:AAD36306.1, ECO:0000313|Proteomes:UP000008183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8
RC {ECO:0000313|Proteomes:UP000008183};
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D., Heidelberg J.,
RA Sutton G.G., Fleischmann R.D., White O., Salzberg S.L., Smith H.O.,
RA Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
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DR EMBL; AE000512; AAD36306.1; -; Genomic_DNA.
DR PIR; H72278; H72278.
DR RefSeq; NP_229036.1; NC_000853.1.
DR RefSeq; WP_004080050.1; NZ_CP011107.1.
DR AlphaFoldDB; Q9X0V8; -.
DR CAZy; GH38; Glycoside Hydrolase Family 38.
DR PaxDb; 243274-THEMA_08175; -.
DR EnsemblBacteria; AAD36306; AAD36306; TM_1231.
DR KEGG; tma:TM1231; -.
DR KEGG; tmw:THMA_1257; -.
DR PATRIC; fig|243274.17.peg.1236; -.
DR InParanoid; Q9X0V8; -.
DR OrthoDB; 9764050at2; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0004559; F:alpha-mannosidase activity; IBA:GO_Central.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR GO; GO:0009313; P:oligosaccharide catabolic process; IBA:GO_Central.
DR CDD; cd10790; GH38N_AMII_1; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008183}.
FT DOMAIN 2..219
FT /note="Glycoside hydrolase family 38 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01074"
SQ SEQUENCE 832 AA; 96627 MW; EFF0B33D0C81A01B CRC64;
MKVKVVVHNH WDREWFTSSE VTSKWLKEVF FRVKELVQKN PEFVYVLDGQ TAAVEDLLVY
HPDLEEDLRE LVRSGRLLVG PYYIQIDWRI PGEASILKNF EIGEKDTNRF GRRMNAGWLL
DSFGHISQEP QLHRIFGIEK VFLWRGISFE NDGISQEFFW KGSDGTAVQG VFLVGGYRNL
YNLKETQDIA EKRLKHEVEK LAKFSRSGEI LLLDGYDIDL SPEDPKDYLN VEIVSPEEFP
ERFPENAPTL SGELLSGRYA CVFPGTLSTR AYLKLESDLV EKLLKMNDLL SVLNGEELSD
LFWRDYLKTL AHDNSCGVCA DPVHEKMERT YRNVYFLVKS SVESRLRHLV ERLGLEKGTY
ALSLSPFSYN HHFCDGERTF LLKTNGAGLF KTEVADEKKE VKELTWENEY YRAYFEGDGT
LVLNNRKAGV LKLFKEDGDA YTTSVEETDF SISLEKMRTV LQTKHSMVVE LERTIRSSQC
LIETKERVIF DETPLVKWRI ALKIKGKNYK LSMVYETGSG EIFAKMPFDV VKRKEKDSYL
LPETPPEELK GILLAARETG EVREFPFQGF VSVWSEESSK TILARGLREY WMEEGKVHVT
LSRSVEWIAK EVKNRVGDAG PMMYVPGAKC EGVFTVDLAF MELPVHPRSE EFFRWYLLFD
NPPLLLDVEA DGTEKEKTFF FSSLPWAGVK DRYHLWVYNP YLEEIEGLRP LQIGEKSIES
LSEKQCFVSR LNILNFPEFP VVSVEKNPEG EVIEFLKETL SSLEDEITNL EGKDDPRSKH
RLFSLLRTKK EIELSLQYLI DVEKTARELN ELRMKRRTYD YVVELFESEE RE
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