ID Q9XWU3_CAEEL Unreviewed; 101 AA.
AC Q9XWU3;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 2.
DT 27-MAR-2024, entry version 160.
DE SubName: Full=LITAF domain-containing protein {ECO:0000313|EMBL:CAA21549.2};
GN ORFNames=CELE_Y41C4A.11 {ECO:0000313|EMBL:CAA21549.2}, Y41C4A.11
GN {ECO:0000313|EMBL:CAA21549.2, ECO:0000313|WormBase:Y41C4A.11};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA21549.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA21549.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA21549.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004630}.
CC -!- SIMILARITY: Belongs to the CDIP1/LITAF family.
CC {ECO:0000256|ARBA:ARBA00005975}.
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DR EMBL; BX284603; CAA21549.2; -; Genomic_DNA.
DR PIR; T26805; T26805.
DR RefSeq; NP_001333540.1; NM_001346633.1.
DR AlphaFoldDB; Q9XWU3; -.
DR STRING; 6239.Y41C4A.11.1; -.
DR EPD; Q9XWU3; -.
DR PeptideAtlas; Q9XWU3; -.
DR EnsemblMetazoa; Y41C4A.11.1; Y41C4A.11.1; WBGene00012757.
DR GeneID; 29991192; -.
DR KEGG; cel:CELE_Y41C4A.11; -.
DR UCSC; Y41C4A.11; c. elegans.
DR AGR; WB:WBGene00012757; -.
DR WormBase; Y41C4A.11; CE51769; WBGene00012757; -.
DR GeneTree; ENSGT00970000196843; -.
DR HOGENOM; CLU_000288_57_31_1; -.
DR InParanoid; Q9XWU3; -.
DR OrthoDB; 2880664at2759; -.
DR PhylomeDB; Q9XWU3; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00012757; Expressed in larva and 3 other cell types or tissues.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; HEP:WormBase.
DR InterPro; IPR006629; LITAF.
DR InterPro; IPR037519; LITAF_fam.
DR PANTHER; PTHR23292; LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR; 1.
DR PANTHER; PTHR23292:SF4; LITAF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10601; zf-LITAF-like; 1.
DR SMART; SM00714; LITAF; 1.
DR PROSITE; PS51837; LITAF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..98
FT /note="LITAF"
FT /evidence="ECO:0000259|PROSITE:PS51837"
SQ SEQUENCE 101 AA; 11480 MW; ECBD47B2135A812C CRC64;
MSYPDDFPIP HVIQPVKVVR HVVKETPIKT PYLDVCPKCQ TTIMTSVTTH IGMCWWLICF
FGTFLFCWPI LICLCFDVSK DVDHNCPNCG LLLATSNRAG F
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