ID Q9XWX5_CAEEL Unreviewed; 1178 AA.
AC Q9XWX5;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 3.
DT 24-JAN-2024, entry version 149.
DE SubName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0000313|EMBL:CAA21511.3};
GN ORFNames=CELE_Y43F8B.3 {ECO:0000313|EMBL:CAA21511.3}, Y43F8B.3
GN {ECO:0000313|EMBL:CAA21511.3, ECO:0000313|WormBase:Y43F8B.3a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA21511.3, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA21511.3, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA21511.3,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; CAA21511.3; -; Genomic_DNA.
DR RefSeq; NP_001123046.2; NM_001129574.2.
DR AlphaFoldDB; Q9XWX5; -.
DR SMR; Q9XWX5; -.
DR MEROPS; I02.955; -.
DR EnsemblMetazoa; Y43F8B.3a.1; Y43F8B.3a.1; WBGene00012814.
DR GeneID; 180277; -.
DR UCSC; Y43F8B.3a; c. elegans.
DR AGR; WB:WBGene00012814; -.
DR WormBase; Y43F8B.3a; CE46772; WBGene00012814; -.
DR GeneTree; ENSGT00940000168743; -.
DR HOGENOM; CLU_008651_0_0_1; -.
DR OrthoDB; 2910701at2759; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00012814; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR ExpressionAtlas; Q9XWX5; baseline and differential.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 3.
DR CDD; cd22593; Kunitz_conkunitzin; 9.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 12.
DR InterPro; IPR006150; Cys_repeat_1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR028150; Lustrin_cystein.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR46339:SF1; PROTEIN CBG05670; 1.
DR PANTHER; PTHR46339; PROTEIN CBG15282-RELATED; 1.
DR Pfam; PF00014; Kunitz_BPTI; 12.
DR Pfam; PF14625; Lustrin_cystein; 8.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 12.
DR SMART; SM00289; WR1; 8.
DR SUPFAM; SSF57362; BPTI-like; 12.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 2.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 12.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q9XWX5};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1178
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004336810"
FT DOMAIN 76..126
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 131..181
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 232..282
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 336..386
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 440..490
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 546..596
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 651..702
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 754..804
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 856..906
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 962..1012
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1067..1117
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1122..1172
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT REGION 38..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1178 AA; 128480 MW; AD261EA31604D374 CRC64;
MPPLRWLFLV LCAVVAVRAA DDSLIGSFKT MFFGNEPEKT NDSATSSQNN PPISYHQYAT
ASSPSSRSQP PSGQSCTLPR QIGTGPYRIP RWYYNPVRGR CELFYWSGCC GNGNNFQTFQ
TCQSTCEVDP CSQDKEPGVG AVQLPRFFFN KDSRICEQFQ YFGTGGNRNN FQTLEECQAQ
CPESPNPCAV TGGATLSPCA PGQGCGTGSY CHVGAQTQTT VCCPKPAAVD RCQQPLNVGI
GNSNLQRWYF NPLTQQCSTC TYRGLQGNEN NFLSQNECEQ SCLVNPCKIG SPYRSQGITV
QCSAMSPTVC PAGHYCHLGA DATTSVCCQA LGNSPCEEEM TQGEGPSALT RFYYDASQRK
CLAFNYLGLK GNRNNFQSKE HCESTCPVWT NPCAIGQPIM TVGQKPFQCH QGATCSTGYF
CHLGYDDATT VCCQSEGDPC SLVVKEGSGN HHLSRWFYNS NTRQCQPFTY TGQGGNENNF
LLREHCEATC PVWINACPSG EPYLLPNGKP QPCDSANVNS CPLTHWCHPG PDASTTMCCP
GKADPCTQTL AQGEGPLSVA RFYFNAQSRT CDEFMFRGLK GNSNNFKSQE DCEKACPVQQ
NPCPITMSSL KHSAKLVPCS ATKSCPSQQW CHYGETKETT VCCPNAVDDP CTAPPRNPGV
GEFHATRWAF DGSARKCVPF EYRGMKGNSN NFLTRENCEK RCPVFQNPCK IGEPHIQNNQ
YMQCSPQQVC PGGHYCHVGT EANYCCKALG GDPCGQPLDR GVGGSQLSRW YWNQQSQCCL
PFSYCGQKGT QNNFLTKQDC DRTCYVFTNP CNQPIALPAT LCSGTGSSDT CGANMWCHIG
ANQDSTVCCP SEGDPCSLPL ARGSGNQFMD RFYYNQQTGS CQQFTYSGLH GNQNNFLTQQ
ACEEQCGPNP CFEGRPFVGA DGRTQTCSAS ANFNTCPLNH WCHIGSDLST TVCCPGASTN
ACNLPMSTGE GNARLDRFYY DQQTKTCRPF VYNGLKGNQN NFISLRACQL SCQPLDNPCI
GQPATTAAGQ VLFCSITNKD SCPVNFWCHI GATPETTVCC PGATNPCSVP LAPGTGNAGL
ARYYYNPDDR QCLPFQYNGK RGNQNNFENQ ADCERTCPEQ LCLLSIDRGA CGGRQTRYAY
NRQTNQCVAF EYTGCGGNLN NFVSIADCQA TCGSVGFR
//
