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Database: UniProt
Entry: Q9Y7Q6
LinkDB: Q9Y7Q6
Original site: Q9Y7Q6 
ID   SET7_SCHPO              Reviewed;         147 AA.
AC   Q9Y7Q6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   16-JAN-2019, entry version 96.
DE   RecName: Full=SET domain-containing protein 7;
DE            EC=2.1.1.43;
GN   Name=set7; ORFNames=SPCC297.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
RA   Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
RA   Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
RA   Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
RA   James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
RA   Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
RA   Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
RA   Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
RA   Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
RA   Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
RA   Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
RA   Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
RA   Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
RA   Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
RA   Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
RA   Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
RA   Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
RA   Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
RA   Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
RA   Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the
RT   fission yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) +
CC         N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:10024, Rhea:RHEA-COMP:9845, Rhea:RHEA-COMP:9846,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:61929; EC=2.1.1.43;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00190}.
DR   EMBL; CU329672; CAB40784.1; -; Genomic_DNA.
DR   PIR; T41271; T41271.
DR   RefSeq; NP_588361.1; NM_001023352.2.
DR   PDB; 5H6Z; X-ray; 2.00 A; A/B=1-147.
DR   PDB; 5WW0; X-ray; 2.10 A; A/B=1-147.
DR   PDBsum; 5H6Z; -.
DR   PDBsum; 5WW0; -.
DR   ProteinModelPortal; Q9Y7Q6; -.
DR   SMR; Q9Y7Q6; -.
DR   STRING; 4896.SPCC297.04c.1; -.
DR   iPTMnet; Q9Y7Q6; -.
DR   MaxQB; Q9Y7Q6; -.
DR   PaxDb; Q9Y7Q6; -.
DR   PRIDE; Q9Y7Q6; -.
DR   EnsemblFungi; SPCC297.04c.1; SPCC297.04c.1:pep; SPCC297.04c.
DR   GeneID; 2539127; -.
DR   KEGG; spo:SPCC297.04c; -.
DR   EuPathDB; FungiDB:SPCC297.04c; -.
DR   PomBase; SPCC297.04c; set7.
DR   HOGENOM; HOG000099050; -.
DR   InParanoid; Q9Y7Q6; -.
DR   KO; K07117; -.
DR   OMA; ATYEINF; -.
DR   PhylomeDB; Q9Y7Q6; -.
DR   PRO; PR:Q9Y7Q6; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000790; C:nuclear chromatin; IC:PomBase.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; TAS:PomBase.
DR   GO; GO:0034968; P:histone lysine methylation; IC:PomBase.
DR   InterPro; IPR009207; A612L_SET_MeTrfase.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   PIRSF; PIRSF022536; A612L_SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Complete proteome; Cytoplasm; Methyltransferase;
KW   Reference proteome; S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    147       SET domain-containing protein 7.
FT                                /FTId=PRO_0000317701.
FT   DOMAIN        8    116       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
FT   STRAND        9     15       {ECO:0000244|PDB:5H6Z}.
FT   TURN         16     18       {ECO:0000244|PDB:5H6Z}.
FT   STRAND       19     26       {ECO:0000244|PDB:5H6Z}.
FT   STRAND       33     42       {ECO:0000244|PDB:5H6Z}.
FT   HELIX        44     49       {ECO:0000244|PDB:5H6Z}.
FT   HELIX        51     53       {ECO:0000244|PDB:5H6Z}.
FT   HELIX        55     58       {ECO:0000244|PDB:5H6Z}.
FT   HELIX        64     66       {ECO:0000244|PDB:5H6Z}.
FT   STRAND       68     71       {ECO:0000244|PDB:5H6Z}.
FT   HELIX        75     77       {ECO:0000244|PDB:5H6Z}.
FT   STRAND       78     80       {ECO:0000244|PDB:5WW0}.
FT   STRAND       85     91       {ECO:0000244|PDB:5H6Z}.
FT   TURN         92     95       {ECO:0000244|PDB:5H6Z}.
FT   STRAND       96    103       {ECO:0000244|PDB:5H6Z}.
FT   STRAND      110    113       {ECO:0000244|PDB:5H6Z}.
SQ   SEQUENCE   147 AA;  17209 MW;  44FBC2EBC2ED3E3D CRC64;
     MRIPVIRSPL EIRDTERKGR GVFALEPIPA QTCIEISPVL MFSKEEYEQH GQYTVLNEYT
     YVWSEGKQGL ALGLGSMFNH DRHPNVYWKK DNRNNYISYY TLREIKTNEE LCISYGDHLW
     FEDEASSASR ISPNEENEDF PLQNISL
//
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