ID Q9Z569_STRCO Unreviewed; 313 AA.
AC Q9Z569;
DT 01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1999, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:CAB37586.1};
GN OrderedLocusNames=SCO5510 {ECO:0000313|EMBL:CAB37586.1};
GN ORFNames=SC8D9.22 {ECO:0000313|EMBL:CAB37586.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB37586.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB37586.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
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DR EMBL; AL939124; CAB37586.1; -; Genomic_DNA.
DR PIR; T35826; T35826.
DR RefSeq; NP_629645.1; NC_003888.3.
DR RefSeq; WP_011030286.1; NZ_VNID01000011.1.
DR AlphaFoldDB; Q9Z569; -.
DR STRING; 100226.gene:17763162; -.
DR PaxDb; 100226-SCO5510; -.
DR PATRIC; fig|100226.15.peg.5596; -.
DR eggNOG; COG0111; Bacteria.
DR HOGENOM; CLU_019796_1_0_11; -.
DR InParanoid; Q9Z569; -.
DR OrthoDB; 4324715at2; -.
DR PhylomeDB; Q9Z569; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0030267; F:glyoxylate reductase (NADP+) activity; IBA:GO_Central.
DR GO; GO:0016618; F:hydroxypyruvate reductase activity; IBA:GO_Central.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd12166; 2-Hacid_dh_7; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 105..277
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 313 AA; 33388 MW; 880DFBB871744053 CRC64;
MTADVWLPIP PDEIEGLPEG PAYRHWDGEE AFPADPADCA FYVVPYMKPS TVGVRPLPGM
RSVQVVQTLS AGIDHVEPGL GHLPAGVRLC NARGVHEAST AELTLALILA SLRGIPDFVR
AQDRGEWLGG FRPALADRTV LIVGYGSIGA AIEDRLVPFE VAPVVRVARS ARTTERGPVH
PLTELPRLLP QADVVILSTP LTEATRGLAG AEFLARMKDG ALLVNVARGP VVDTKALLAE
LESGRLTAAL DVTDPEPLPP GHPLWHAPGI VVSPHAGGPT SAFLPRAERL LVDQLTRFVN
REPLRNVILT TGS
//
