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Database: UniProt
Entry: Q9ZEA1
LinkDB: Q9ZEA1
Original site: Q9ZEA1 
ID   SDHB_RICPR              Reviewed;         261 AA.
AC   Q9ZEA1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   05-DEC-2018, entry version 114.
DE   RecName: Full=Succinate dehydrogenase iron-sulfur subunit;
DE            EC=1.3.5.1;
GN   Name=sdhB; OrderedLocusNames=RP044;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O.,
RA   Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K.,
RA   Eriksson A.-S., Winkler H.H., Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + succinate = a quinol + fumarate;
CC         Xref=Rhea:RHEA:40523, ChEBI:CHEBI:24646, ChEBI:CHEBI:29806,
CC         ChEBI:CHEBI:30031, ChEBI:CHEBI:132124; EC=1.3.5.1;
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:49601;
CC       Note=Binds 1 [2Fe-2S] cluster.;
CC   -!- COFACTOR:
CC       Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC       Note=Binds 1 [3Fe-4S] cluster.;
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC       Note=Binds 1 [4Fe-4S] cluster.;
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       fumarate from succinate (bacterial route): step 1/1.
CC   -!- SUBUNIT: Part of an enzyme complex containing four subunits: a
CC       flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic
CC       anchor protein.
CC   -!- SIMILARITY: Belongs to the succinate dehydrogenase/fumarate
CC       reductase iron-sulfur protein family. {ECO:0000305}.
DR   EMBL; AJ235270; CAA14515.1; -; Genomic_DNA.
DR   PIR; D71712; D71712.
DR   RefSeq; NP_220438.1; NC_000963.1.
DR   RefSeq; WP_004596634.1; NC_000963.1.
DR   ProteinModelPortal; Q9ZEA1; -.
DR   SMR; Q9ZEA1; -.
DR   STRING; 272947.RP044; -.
DR   EnsemblBacteria; CAA14515; CAA14515; CAA14515.
DR   GeneID; 883577; -.
DR   KEGG; rpr:RP044; -.
DR   PATRIC; fig|272947.5.peg.45; -.
DR   eggNOG; ENOG4105E33; Bacteria.
DR   eggNOG; COG0479; LUCA.
DR   HOGENOM; HOG000160590; -.
DR   KO; K00240; -.
DR   OMA; DGQYFGP; -.
DR   BioCyc; RPRO272947:G1GT0-44-MONOMER; -.
DR   UniPathway; UPA00223; UER01005.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   CDD; cd00207; fer2; 1.
DR   Gene3D; 1.10.1060.10; -; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR   InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR   InterPro; IPR006058; 2Fe2S_fd_BS.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR004489; Succ_DH/fum_Rdtase_Fe-S.
DR   InterPro; IPR025192; Succ_DH/fum_Rdtase_N.
DR   Pfam; PF13085; Fer2_3; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   SUPFAM; SSF54292; SSF54292; 1.
DR   TIGRFAMs; TIGR00384; dhsB; 1.
DR   PROSITE; PS00197; 2FE2S_FER_1; 1.
DR   PROSITE; PS51085; 2FE2S_FER_2; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   2Fe-2S; 3Fe-4S; 4Fe-4S; Complete proteome; Electron transport; Iron;
KW   Iron-sulfur; Metal-binding; Oxidoreductase; Reference proteome;
KW   Transport; Tricarboxylic acid cycle.
FT   CHAIN         1    261       Succinate dehydrogenase iron-sulfur
FT                                subunit.
FT                                /FTId=PRO_0000158691.
FT   DOMAIN       28    119       2Fe-2S ferredoxin-type.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00465}.
FT   DOMAIN      161    191       4Fe-4S ferredoxin-type.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00711}.
FT   METAL        80     80       Iron-sulfur 1 (2Fe-2S). {ECO:0000250}.
FT   METAL        85     85       Iron-sulfur 1 (2Fe-2S). {ECO:0000250}.
FT   METAL       100    100       Iron-sulfur 1 (2Fe-2S). {ECO:0000250}.
FT   METAL       171    171       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL       174    174       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL       177    177       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL       181    181       Iron-sulfur 3 (3Fe-4S). {ECO:0000250}.
FT   METAL       228    228       Iron-sulfur 3 (3Fe-4S). {ECO:0000250}.
FT   METAL       234    234       Iron-sulfur 3 (3Fe-4S). {ECO:0000250}.
FT   METAL       238    238       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   BINDING     186    186       Ubiquinone; shared with SdhD subunit.
FT                                {ECO:0000250}.
SQ   SEQUENCE   261 AA;  29572 MW;  AFAB638FFF0F44A1 CRC64;
     MVELRLPSNS VVKKGREHKA QQKMLKPRKV KVYRYDPDLD ENPTIDSFEI DLSKTGPMVL
     DALIKIKNEI DSTLTFRRSC REGICGSCAM NIDGTNTLAC IKPIEDISGD IKIYPLPHMK
     VVKDLVPDMS HFYAQYESIE PWLKNDSPAP SNSERLQSIK DREKLDGLYE CILCACCSTS
     CPSYWWNGDK YLGPAILLQA YRWIADSRDD NTGARLEALE DPFKLYRCHT IMNCTKTCPK
     GLNPAKAIGR VKNLIAERHG V
//
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