ID R0A5P2_9FIRM Unreviewed; 648 AA.
AC R0A5P2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Fis family proprionate catabolism activator {ECO:0000313|EMBL:ENZ47406.1};
GN ORFNames=HMPREF1085_04585 {ECO:0000313|EMBL:ENZ47406.1};
OS Enterocloster bolteae 90A9.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Enterocloster.
OX NCBI_TaxID=997894 {ECO:0000313|EMBL:ENZ47406.1, ECO:0000313|Proteomes:UP000013126};
RN [1] {ECO:0000313|EMBL:ENZ47406.1, ECO:0000313|Proteomes:UP000013126}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90A9 {ECO:0000313|EMBL:ENZ47406.1,
RC ECO:0000313|Proteomes:UP000013126};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium bolteae 90A9.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ47406.1}.
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DR EMBL; AGYH01000016; ENZ47406.1; -; Genomic_DNA.
DR RefSeq; WP_002577340.1; NZ_KB851182.1.
DR AlphaFoldDB; R0A5P2; -.
DR PATRIC; fig|997894.4.peg.4782; -.
DR HOGENOM; CLU_000445_8_1_9; -.
DR OrthoDB; 9764280at2; -.
DR Proteomes; UP000013126; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.10660; PrpR receptor domain-like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF06506; PrpR_N; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 317..542
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT COILED 174..201
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 648 AA; 71988 MW; CB5DE2E79C05CEF7 CRC64;
MSQIWYAAFS EDFVGQAQKI FKKLDKDVIV TVWDPELVPE MLRRGVSVIL GRGATALRIR
KVVDLPVVEI PIPFEDMADT LIEASRYGRN IGVIGYNNLL SGLECLNPIL NVSIRQIFAV
DENDTYHQIQ KLKNEGIDVI VGGLLQTHYA RELGLPAVRI ELTDKSLSYA CQEAEKLIAT
VKAATRKAEE LKTILNTTNE KYVAVDIKGN ITWMNRVAKP YLPNPGGLVY DTPITEVLPA
FEAVHDVLAT GEEIIQETGS INGADILYDM IPLTYKNGEI LGAVITFNDA GTITRGEHKI
RDKGIKGFQA TYSFKDICGS SQQMNQCIQH AKRYAHTDLT VLLLGETGSG KEMFAQSMHN
ASSRRNGPFV AVNCAALPEG ILESELFGYD DGAFTGARRS GKMGLFELAH NGTIFLDEIG
EMPMSLQSRL LRVLQERKVM RLGGDRVFPV NIRIFAATNK NLMELVGEHK FREDLFYRLN
VLTLKIPPLR ERVEDIPDLA NLFLRESGGK CCLTPAAENM LTSYGWPGNA RQLRHFMEKV
RIICDSSVIS GEAAGYVIQN YEPPCEMEQR GNSSGFLGSN GIGNYKATKG RVNRSQEEPG
QENISREITE ACLAQAIEQA GGNKTEAARI LGIHRSTIWR YIKKFGME
//
