ID R0BN13_9FIRM Unreviewed; 495 AA.
AC R0BN13;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Multicomponent Na+:H+ antiporter subunit D {ECO:0000313|EMBL:ENZ46309.1};
GN ORFNames=HMPREF1085_04892 {ECO:0000313|EMBL:ENZ46309.1};
OS Enterocloster bolteae 90A9.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Enterocloster.
OX NCBI_TaxID=997894 {ECO:0000313|EMBL:ENZ46309.1, ECO:0000313|Proteomes:UP000013126};
RN [1] {ECO:0000313|EMBL:ENZ46309.1, ECO:0000313|Proteomes:UP000013126}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90A9 {ECO:0000313|EMBL:ENZ46309.1,
RC ECO:0000313|Proteomes:UP000013126};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium bolteae 90A9.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A
CC family. {ECO:0000256|ARBA:ARBA00008483}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ46309.1}.
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DR EMBL; AGYH01000018; ENZ46309.1; -; Genomic_DNA.
DR RefSeq; WP_002577574.1; NZ_KB851182.1.
DR AlphaFoldDB; R0BN13; -.
DR PATRIC; fig|997894.4.peg.5108; -.
DR HOGENOM; CLU_007100_9_3_9; -.
DR OrthoDB; 9807568at2; -.
DR Proteomes; UP000013126; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR42682:SF3; HYDROGENASE-4 COMPONENT B; 1.
DR PANTHER; PTHR42682; HYDROGENASE-4 COMPONENT F; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..108
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 124..416
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 495 AA; 53204 MW; 0257EC5ED95E0DBB CRC64;
MREMWMMAPV LFPVVSGGAL WIWNPGKNKI HTAAAVLSLA EAVCSWLVIL NCMGMKLPLW
SIGPGLELCL RLDGTGALFS GLASLIWVLV VFFAFEYMEH EKEDARFFGC LIMSLGALTG
VAWAGNFVTL YLFFEMMTFF SVPLVFHSRK REALRAGMVY LAYSMLGASI ALGGYFFFRQ
YACGTDFKAG GVLAEAAGMA RGRPQILLLA VFFMAAGFSC KAGLMPLHPW LPIAHPVAPA
PASAVLSGLI TKAGVVAVIR VVYNMAGPAF LRGTWVQYAL LSMAVVTIFT GSMLAYKEKK
LKRRLACSSF SQVSYVLLGV FLLSMEGLYG SLLQMVFHAL AKNALFLCAG AVICKTGCTR
VKELRGMGKR MPAVMVCFAL ASLSLVGIPP AGGFLAKWHL AVGAMRAEAG VFAWLGPVVL
MVSALLTAGY LFPVIVEGFF PGEDWRKTAQ SEDGRLSVSA FMGVPLAVLG ISLLVLGALG
NPVFELLRGI ASDMV
//
