ID R0BS19_9FIRM Unreviewed; 850 AA.
AC R0BS19;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:ENZ51438.1};
GN ORFNames=HMPREF1085_01632 {ECO:0000313|EMBL:ENZ51438.1};
OS Enterocloster bolteae 90A9.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Enterocloster.
OX NCBI_TaxID=997894 {ECO:0000313|EMBL:ENZ51438.1, ECO:0000313|Proteomes:UP000013126};
RN [1] {ECO:0000313|EMBL:ENZ51438.1, ECO:0000313|Proteomes:UP000013126}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90A9 {ECO:0000313|EMBL:ENZ51438.1,
RC ECO:0000313|Proteomes:UP000013126};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium bolteae 90A9.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ51438.1}.
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DR EMBL; AGYH01000004; ENZ51438.1; -; Genomic_DNA.
DR RefSeq; WP_002574972.1; NZ_KB851182.1.
DR AlphaFoldDB; R0BS19; -.
DR PATRIC; fig|997894.4.peg.1734; -.
DR HOGENOM; CLU_000445_36_0_9; -.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000013126; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 2.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 2.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204}.
FT DOMAIN 9..51
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 159..295
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 456..588
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 597..850
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 850 AA; 98160 MW; 9008E259275818C0 CRC64;
MEEQQHLFKD TFLAAVLDQM DTNFYITDVE TDEILYMNKT MKETFGLARP EGCICWQVLQ
KDMKERCPYC KIRQLEQMED NRICIWRETN SVTGRKYRNY DSLIQWKGKV YHIQNSVDMT
EFDQISETAR TDELTRMLNR RGGGERLRQA LEQGGRENQV VTVVLYDINE LKAVNDRYGH
SEGDRLLQYV AAIAKECLGR LDFMYRLSGD EFVMVFYGRD MKAADDSMKR LLSRAGQERK
HLRKEYDVSF SYGIAEVYPG DMGSVEDIIS RADEQMYVQK RGYHIERARR RLREKSEGRD
ETFDYDGECL YEALSASTDD YIFVGNMKTG VFRYPQSMAE EFGLPGQVVR EAAAFWGQLI
HPHDEAYFLE SNQSIADGRE DYHNIEYRAR NVRGEWIWLR CRGKMLRDKD GQPELFAGMI
SNLGKKNQID HMTGLYNKYE FEGNIKKYLA DRKCMDSIGL MVLDMDSFKN INDLYDRSFG
DEVLRITAQK VASMLPPNAM LYRLDGDEFG ILLLGGDAKE AAHIYGKLQK NFCKQQEYGG
KKYFCTLSAG YAAYPGDGSN YLELLKSANY SLEYSKIMGK NRMTVFSRDI LADRERRLEL
LELLRESVER GFAGFTIHYQ PQVDTVSGRL CGAEALARWH CTKYGDVSPG EFIPLMEQSG
LIIPFGQWIL SRGMAQCLEW CRFRPDFQIS VNLSYIQLAQ GDFISFLRTA LEEHSLAPSK
IILELTETYL AKAEEDTLRM IAQMKELGVK IAMDDFGVGY SSLFSLKSIP VDVVKIDRGF
VKGITSDLFN ATFIRSITDL CHDVGRKVCL EGVETEEEYE AVRELGMEYI QGYYFGRPMS
ARQFEDRLKE
//
