ID   R0C4S7_9FIRM            Unreviewed;       246 AA.
AC   R0C4S7;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Thiamin-thiazole moiety synthesis protein ThiF {ECO:0000313|EMBL:ENZ51567.1};
GN   ORFNames=HMPREF1085_01762 {ECO:0000313|EMBL:ENZ51567.1};
OS   Enterocloster bolteae 90A9.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Enterocloster.
OX   NCBI_TaxID=997894 {ECO:0000313|EMBL:ENZ51567.1, ECO:0000313|Proteomes:UP000013126};
RN   [1] {ECO:0000313|EMBL:ENZ51567.1, ECO:0000313|Proteomes:UP000013126}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=90A9 {ECO:0000313|EMBL:ENZ51567.1,
RC   ECO:0000313|Proteomes:UP000013126};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium bolteae 90A9.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ENZ51567.1}.
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DR   EMBL; AGYH01000004; ENZ51567.1; -; Genomic_DNA.
DR   RefSeq; WP_002575083.1; NZ_KB851182.1.
DR   AlphaFoldDB; R0C4S7; -.
DR   PATRIC; fig|997894.4.peg.1872; -.
DR   HOGENOM; CLU_013325_4_1_9; -.
DR   OrthoDB; 9804150at2; -.
DR   Proteomes; UP000013126; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd00755; YgdL_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
FT   DOMAIN          6..244
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   246 AA;  26481 MW;  60B91170F41625E7 CRC64;
     MINEFSRTEM LIGTEGMNKL KNSTVVLFGV GGVGSHAAEA LARCGVGRLI LVDNDTVSLT
     NINRQSIALH STMGQFKTRV MKDKIADICP GTQVITFEEF VLPDNIESLF ERMKHQMGQG
     NSVDYILDAI DTVTAKLALA GFAASHAIPV IASMGTGNKL HPELFRISDI SQTSVCPLCK
     VMRRELKARN IRGLKVCWSP EQPLTPGQTA EDTGCRRATP GSISFVPPVA GLVIAGEIIR
     DICGLA
//