ID R0EPR8_CAUVI Unreviewed; 465 AA.
AC R0EPR8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Na+/melibiose symporter-like transporter {ECO:0000313|EMBL:ENZ83829.1};
DE Flags: Precursor;
GN ORFNames=OR37_00337 {ECO:0000313|EMBL:ENZ83829.1};
OS Caulobacter vibrioides OR37.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=1292034 {ECO:0000313|EMBL:ENZ83829.1, ECO:0000313|Proteomes:UP000013063};
RN [1] {ECO:0000313|EMBL:ENZ83829.1, ECO:0000313|Proteomes:UP000013063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR37 {ECO:0000313|EMBL:ENZ83829.1,
RC ECO:0000313|Proteomes:UP000013063};
RX PubMed=23792749;
RA Utturkar S.M., Bollmann A., Brzoska R.M., Klingeman D.M., Epstein S.E.,
RA Palumbo A.V., Brown S.D.;
RT "Draft Genome Sequence for Caulobacter sp. Strain OR37, a Bacterium
RT Tolerant to Heavy Metals.";
RL Genome Announc. 1:0-0(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ83829.1}.
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DR EMBL; APMP01000001; ENZ83829.1; -; Genomic_DNA.
DR RefSeq; WP_004615402.1; NZ_APMP01000001.1.
DR AlphaFoldDB; R0EPR8; -.
DR STRING; 1292034.OR37_00337; -.
DR PATRIC; fig|1292034.3.peg.333; -.
DR eggNOG; COG2211; Bacteria.
DR OrthoDB; 9764596at2; -.
DR Proteomes; UP000013063; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd17332; MFS_MelB_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR018043; Na/Gal_symport_CS.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 465 AA; 49755 MW; 3D253D85786412E4 CRC64;
MTDRRPSWAL AAFATPCIPI AAMGLPLVVY LPEFYVSSLG LSLSAVGAAF LVVKLVDIFF
DPILGGMMDR TRTRLGRFRP WLIAGTPVIV AGSYFLFMAQ PGVGPVYLWF WLVVVYGGYS
MVVLSQTAWG AVLSSDYQQR SRVYGWWQAG NVVGMILVLC LPPIVTGVFK GDHLASVQAM
GWFVVILAPL STLLATTLVG EPEAPKVVHK AGLREYAALF KRPSVRLLLT ADILMGLAPG
IAGSLFIFFF ERIKHLDKTQ SGVLLLVYFV AALAGAPIWP FLAKRLGKHR ALSVAAIAYA
VFQIAAAMTP TGFTWIGTLS LILSGLPYSA APLLVRSMMA DIGDEERLAS GADRTGLLYA
IVSGAMKLGY ALAVGVFIVL SWMGFDPKAP TASGDAALIG LFAFLPAGLG LLVSVVMLRY
PLDAQRLAEI QRQLAARDAV TVQTPPAAEP DPNVSVLPVD IAPAK
//
