ID R0FAS4_9BRAS Unreviewed; 339 AA.
AC R0FAS4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=WAT1-related protein {ECO:0000256|RuleBase:RU363077};
GN ORFNames=CARUB_v10007791mg {ECO:0000313|EMBL:EOA19122.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA19122.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363077}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU363077}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000256|ARBA:ARBA00007635, ECO:0000256|RuleBase:RU363077}.
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DR EMBL; KB870811; EOA19122.1; -; Genomic_DNA.
DR RefSeq; XP_006286224.1; XM_006286162.1.
DR AlphaFoldDB; R0FAS4; -.
DR STRING; 81985.R0FAS4; -.
DR GeneID; 17878097; -.
DR KEGG; crb:17878097; -.
DR OrthoDB; 938873at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; WAT1-RELATED PROTEIN; 1.
DR PANTHER; PTHR31218:SF304; WAT1-RELATED PROTEIN; 1.
DR Pfam; PF00892; EamA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363077};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transmembrane {ECO:0000256|RuleBase:RU363077};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363077}.
FT TRANSMEM 43..68
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 80..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 109..128
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 140..158
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 210..232
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT DOMAIN 25..158
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 339 AA; 36918 MW; 61961EE76637CC5F CRC64;
MREDTVAWKY FKRDVVPFAA MVAVECTTVG SSTLYKAATL RGFSFYVFVF YSYVGATLVL
LLLSLIFGRS RSLPSAKSPL FFKIFLLALL GLTSRVAGCK GIEYSSPTLS SAISNLTPAF
TFMLAIFFRM EQVVLRSSAT QAKIIGTVVS ISGALVIVLY KGPKLLVAAS FTSFESSWIT
GGLLLGLQFL LLSVWFILQT HIMEIYPEEI AVVFCYNLCA MFISGTVCLI VEKDLNSWQL
KPGFALASVI YSGIFDTSLG SVIHTWGLHV KGPVYVSLFK PLSIAIAVAM SAIFLGDALH
LGSVIGSVIL SFGFYTVIWG KAREDATKTV SDSEQPLLL
//
