ID R0FLB3_9BRAS Unreviewed; 258 AA.
AC R0FLB3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
GN ORFNames=CARUB_v10003485mg {ECO:0000313|EMBL:EOA22771.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA22771.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000256|RuleBase:RU910715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU910715};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU910715}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR EMBL; KB870810; EOA22771.1; -; Genomic_DNA.
DR RefSeq; XP_006289873.1; XM_006289811.1.
DR AlphaFoldDB; R0FLB3; -.
DR STRING; 81985.R0FLB3; -.
DR GeneID; 17882219; -.
DR KEGG; crb:17882219; -.
DR eggNOG; KOG1623; Eukaryota.
DR OrthoDB; 73377at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR10791:SF30; SUGAR TRANSPORTER SWEET1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU910715};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 47..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
SQ SEQUENCE 258 AA; 28405 MW; BF9C1BC55290CC8F CRC64;
MGFAHLNLVR KIVGIIGNFI ALCLFLSPTP TFVGIVKKKS VEAYSPIPYL ATLINCMVWV
LYGLPKVHPD STLVLTINGT GIAIEIVFLA IFFIYCGHKK QRLAIAAVLA GETALVAILA
VLVFTLQHTT DQRTMSVGIV CCVFNVMMYA SPLSVMKMVI KTKSVEFMPF WLSFAAFLNA
GVWTIYALMP FDPFIAIPNG IGCVFGLGQL ILYGAYYKST KKIMAERQEQ PGYIDLSTAV
ARTESEKLEN FNKQIIGV
//
