ID R0G0I9_9BRAS Unreviewed; 901 AA.
AC R0G0I9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=CARUB_v10024900mg {ECO:0000313|EMBL:EOA28676.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA28676.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; KB870808; EOA28676.1; -; Genomic_DNA.
DR RefSeq; XP_006295778.1; XM_006295716.1.
DR AlphaFoldDB; R0G0I9; -.
DR STRING; 81985.R0G0I9; -.
DR eggNOG; KOG0987; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 738..784
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 901 AA; 104049 MW; 11FE99A261D22BDF CRC64;
MHGPCGPKCM DDNKCTKKFP RPYNDTTNIS EAGYITYRRR YDETKFVMKG NTRLDNHYVV
PHNLDLLKKY KAHINVEWCN RSTTIKYLFK YITKGVDMAT MKIKRKQAVD RNKEESESQE
EINEIKNYLE CRYLSACEAT WRIFAFDIHE RKPAVTRLSL HLPNQQRITY PEGARLEYIL
SKEGIDKTML TEWFEMNKRC PEARKLTYIQ FPTYYVWDSD GKMWSERKQG FSIGRIVNIH
PTAGDLYYLR MLLNTEKGPT SFDDLLTVEN VKHKTFKAAC YARGMLNGDS EWKEAMDEAA
EYAYPFQLRH LFVTLLIYCE LSSPLTLWEH CWRHLAEDIP NNQRKIFNFG DQKFTTEELQ
SYTLIEIEKI LAQNDRSLTD FEDMPKPDKE LLKKIKNSML QDETSYNILK EEKDYRRLIQ
TLNDDQKKVY DAVIDSIEHQ KGKLFFLNGP GGTGKTYVYK TIISRLRSQR KIVLPVASSG
IAATLLPNGR TAHSRFKIPI DLHQDSICNI SRGSMLAELL EKTDLIIWDE APMCHRFAFE
ALDKSLRDLL SVADPNAASK PFGGKTVLLG SDFRQILPVI PQGTRQETVM ATITRSYLWN
YISIFTLEKN MRLHQAEKEF ANWLIGIGDG TIPKPEKYRT LSDEIGIVEI ENNLLLPNNG
DSVSCIATSI YHDFDANFKN KGYLIERAIL TPRNETVDEV NNYMLSCLKG EQKEYLSSDT
IGDDKEEVAN QHILYPTDFL NTLKFSGIPN HKLDLKIDAP IMLLRNINQR EGLCNGTRLI
ITRLGKRIIE AEILTGTHVG KRVLIPRISL TPTDAKWPFK LKRRQFPVRV CYAMTINKSQ
GQSLNNVGLY LPSPVFSHGQ LYVALSRVTT TAGLKILKGD TKYYDNNVLH NIVYQEVFNN
I
//
